NCT02720315

Brief Summary

Acute musculoskeletal (MSK) injuries, including strains, sprains or contusions, are a common reason patients seek emergency care. Pain control is an essential component of treatment. Within the orthopedic literature, there is robust body of research supporting the use of cryotherapy for post-operative patients and injured athletes. However, within the emergency department (ED), studies have been focused on pharmacologic analgesia. The absence of evidence on optimal method or impact of ice therapy for acute MSK injuries contributes to inconsistent practice patterns that may impede symptom control or increase narcotic usage. The specific aim of the ICED investigation is to evaluate the effectiveness of intensive cryotherapy for the treatment of pain due to acute MSK injuries treated in the ED. Secondary outcomes include length-of-stay (LOS), patient satisfaction, and narcotic usage.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
38

participants targeted

Target at below P25 for not_applicable pain

Timeline
Completed

Started Feb 2016

Longer than P75 for not_applicable pain

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2016

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

March 10, 2016

Completed
15 days until next milestone

First Posted

Study publicly available on registry

March 25, 2016

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 28, 2017

Completed
2.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 30, 2019

Completed
Last Updated

November 6, 2019

Status Verified

November 1, 2019

Enrollment Period

1.1 years

First QC Date

March 10, 2016

Last Update Submit

November 3, 2019

Conditions

Outcome Measures

Primary Outcomes (2)

  • Change in pain level

    20 minutes

  • Change in pain level

    60 minutes

Secondary Outcomes (1)

  • Change in analgesic utilization

    24hr

Study Arms (2)

Intensive cryotherapy

EXPERIMENTAL

Application of ice in a plastic bag wrapped to the patient's site of pain, and kept in place for 20min.

Procedure: Intensive cryotherapy

Control

NO INTERVENTION

Existing pain control practice of physicians and nurses, which includes application of a chemical cold pack.

Interventions

Application of ice inside a plastic bag wrapped to the patient's site of pain, and held in place for 20min.

Intensive cryotherapy

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • all people presenting to the ED with musculoskeletal injuries

You may not qualify if:

  • Patients with hip fractures
  • Patients with open fractures
  • Patients with altered mental status who are unable to consent to participate in the study
  • Patients activated as a trauma
  • Patients with fractures or dislocations requiring closed reduction in the emergency department
  • Minors
  • Prisoners
  • Patients with known pregnancy
  • Patient who are receiving investigational drug as part of another study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

PainEmergencies

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsDisease AttributesPathologic Processes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Chief Resident

Study Record Dates

First Submitted

March 10, 2016

First Posted

March 25, 2016

Study Start

February 1, 2016

Primary Completion

February 28, 2017

Study Completion

October 30, 2019

Last Updated

November 6, 2019

Record last verified: 2019-11

Data Sharing

IPD Sharing
Will not share