NCT02717338

Brief Summary

The purpose of this study is to determine whether enhancing blood donor competence, autonomy, and/or relatedness increases intrinsic motivation to donate and improves donor retention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,580

participants targeted

Target at P75+ for phase_3

Timeline
Completed

Started May 2016

Longer than P75 for phase_3

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 18, 2016

Completed
1 month until next milestone

First Posted

Study publicly available on registry

March 23, 2016

Completed
2 months until next milestone

Study Start

First participant enrolled

May 27, 2016

Completed
4.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2020

Completed
Last Updated

March 3, 2022

Status Verified

February 1, 2022

Enrollment Period

4.6 years

First QC Date

February 18, 2016

Last Update Submit

February 15, 2022

Conditions

Keywords

blood donorretentionmotivationself-determination theory

Outcome Measures

Primary Outcomes (1)

  • Repeat Blood Donation Attempts

    Donor records will be used to track all instances of subsequent donation attempts during the one-year follow-up.

    one year plus 8 weeks post-initial donation

Secondary Outcomes (14)

  • Blood Donation Attitude

    Pre-intervention (requested 1-2 weeks post-donation) and Post-intervention (requested 7 weeks post-donation)

  • Blood Donation Subjective Norms

    Pre-intervention (requested 1-2 weeks post-donation) and Post-intervention (requested 7 weeks post-donation)

  • Blood Donation Perceived Behavioral Control

    Pre-intervention (requested 1-2 weeks post-donation) and Post-intervention (requested 7 weeks post-donation)

  • Blood Donation Intention

    Pre-intervention (requested 1-2 weeks post-donation) and Post-intervention (requested 7 weeks post-donation)

  • Blood Donation Personal Moral Norm

    Pre-intervention (requested 1-2 weeks post-donation) and Post-intervention (requested 7 weeks post-donation)

  • +9 more secondary outcomes

Study Arms (8)

Competence

EXPERIMENTAL

Participants will be assigned to review our donor coping website.

Behavioral: Competence

Autonomy

EXPERIMENTAL

Participants will be assigned to receive a brief telephone interview.

Behavioral: Autonomy

Relatedness

EXPERIMENTAL

Participants will be asked to join a closed Facebook group for one month.

Behavioral: Relatedness

Competence + Autonomy

EXPERIMENTAL

Participants will be assigned to the web site review, followed by the brief telephone interview.

Behavioral: CompetenceBehavioral: Autonomy

Competence + Relatedness

EXPERIMENTAL

Participants will be assigned to the web site review, followed by the one-month Facebook group membership.

Behavioral: CompetenceBehavioral: Relatedness

Autonomy + Relatedness

EXPERIMENTAL

Participants will be assigned to the brief telephone interview, followed by the one-month Facebook group membership.

Behavioral: AutonomyBehavioral: Relatedness

Competence + Autonomy + Relatedness

EXPERIMENTAL

Participants will be assigned to the web site review, brief telephone interview, and one-month Facebook group membership.

Behavioral: CompetenceBehavioral: AutonomyBehavioral: Relatedness

Treatment-as-Usual Control

NO INTERVENTION

Participants will receive the standard communications that New York Blood Center has with all first-time donors.

Interventions

CompetenceBEHAVIORAL

Participants will be assigned to review our donor coping website that combines text, videos, and interactive features to directly address common donor fears and to offer advice on empirically-validated strategies to reduce fear, pain, and syncopal reactions.

CompetenceCompetence + AutonomyCompetence + Autonomy + RelatednessCompetence + Relatedness
AutonomyBEHAVIORAL

Participants will be assigned to receive a brief telephone interview that we have developed that encourages blood donors to reflect upon their unique motivations for giving and how the act of donating is consistent with their broader life goals and values.

AutonomyAutonomy + RelatednessCompetence + AutonomyCompetence + Autonomy + Relatedness
RelatednessBEHAVIORAL

Participants will be asked to join a closed Facebook group for one month. The group encourages participants to discuss their experiences with blood donation, including such things as posting images of their donations and/or reasons for donating. Posts will be designed to encourage social interaction around donation experiences, identity formation and group affiliation.

Autonomy + RelatednessCompetence + Autonomy + RelatednessCompetence + RelatednessRelatedness

Eligibility Criteria

Age16 Years - 24 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • First-time whole blood donor with New York Blood Center;
  • Eligible to donate again;
  • Willing to be randomly assigned;
  • Have, or be willing to establish, an active Facebook account.

You may not qualify if:

  • History of more than one lifetime whole blood donation (with any blood center);
  • Ineligible to donate again (based on New York Blood Center donor eligibility determination);
  • Unwilling to be randomly assigned;
  • Unwilling to sign up for closed Facebook group, if randomly assigned.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ohio University

Athens, Ohio, 45701, United States

Location

Related Publications (3)

  • France CR, France JL, Himawan LK, Fox KR, Livitz IE, Ankawi B, Slepian PM, Kowalsky JM, Duffy L, Kessler DA, Rebosa M, Rehmani S, Frye V, Shaz BH. Results from the blood donor competence, autonomy, and relatedness enhancement (blood donor CARE) randomized trial. Transfusion. 2021 Sep;61(9):2637-2649. doi: 10.1111/trf.16577. Epub 2021 Jul 5.

  • Frye V, Duffy L, France JL, Kessler DA, Rebosa M, Shaz BH, Carlson BW, France CR. The Development of a Social Networking-Based Relatedness Intervention Among Young, First-Time Blood Donors: Pilot Study. JMIR Public Health Surveill. 2018 Apr 26;4(2):e44. doi: 10.2196/publichealth.8972.

  • France CR, France JL, Carlson BW, Frye V, Duffy L, Kessler DA, Rebosa M, Shaz BH. Applying self-determination theory to the blood donation context: The blood donor competence, autonomy, and relatedness enhancement (Blood Donor CARE) trial. Contemp Clin Trials. 2017 Feb;53:44-51. doi: 10.1016/j.cct.2016.12.010. Epub 2016 Dec 12.

MeSH Terms

Interventions

Mental CompetencyPhylogeny

Intervention Hierarchy (Ancestors)

JurisprudenceSocial Control, FormalHealth Care Economics and OrganizationsBiological EvolutionGenetic PhenomenaBiological Phenomena

Study Officials

  • Christopher R. France, Ph.D.

    Ohio University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Distinguished Professor

Study Record Dates

First Submitted

February 18, 2016

First Posted

March 23, 2016

Study Start

May 27, 2016

Primary Completion

December 31, 2020

Study Completion

December 31, 2020

Last Updated

March 3, 2022

Record last verified: 2022-02

Data Sharing

IPD Sharing
Will share

Following publication of our findings, the raw and processed data will be freely available to any researcher who requests a copy. The raw data files will be stored as EXCEL and SPSS data files and will be de-identified so there is no possibility of connecting the information with the original participants. To obtain access to the data, interested parties can contact the PI.

Shared Documents
STUDY PROTOCOL, ICF
Time Frame
De-identified data will be made available one year after publication of the study findings.
Access Criteria
A controlled access approach will be used to share de-identified data with individuals who 1) make an official request to the Principal Investigator, 2) demonstrate a legitimate academic purpose for the request, 3) provide evidence of up-to-date compliance with human subjects ethics training, and 4) agree to delete the data within an agreed-upon timeframe and not share the data with others.

Locations