NCT02717026

Brief Summary

Retinal blood flow measurement is of scientific and clinical value. For this purpose retinal vessel morphology (such as diameter, vessel wall thickness, etc) determination is crucial. Different imaging modalities might provide divergent results. Thus, quantification of such differences is valuable. The present study aims to reveal and quantify differences in vessel morphology between fundus photography, fundus angiography, and optical coherence tomography in health and disease.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jul 2015

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2015

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

September 7, 2015

Completed
7 months until next milestone

First Posted

Study publicly available on registry

March 23, 2016

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2017

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2018

Completed
Last Updated

September 14, 2020

Status Verified

September 1, 2020

Enrollment Period

2.4 years

First QC Date

September 7, 2015

Last Update Submit

September 11, 2020

Conditions

Retinal Blood VesselsAge-Related Macular Degeneration

Outcome Measures

Primary Outcomes (1)

  • retinal vessel diameter

    5 minutes

Secondary Outcomes (1)

  • retinal vessel reflectivity

    5 minutes

Interventions

Optical coherence tomographyDEVICE

Sections including the retinal vasculature will be taken.

Fluorescein angiographyDEVICE

Video fluorescein angiography from one eye of each subject will be performed

Fundus photographyDEVICE

30 and 50 degree fundus images

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

adult patients scheduled for routine retinal assessment

You may qualify if:

  • written informed consent, clear media

You may not qualify if:

  • any abnormality preventing reliable vessel measurement, pregnancy,

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Ophthalmology, Medical University of Graz

Graz, Styria, 8036, Austria

Location

MeSH Terms

Conditions

Macular Degeneration

Interventions

Tomography, Optical CoherenceFluorescein Angiography

Condition Hierarchy (Ancestors)

Retinal DegenerationRetinal DiseasesEye Diseases

Intervention Hierarchy (Ancestors)

Tomography, OpticalOptical ImagingDiagnostic ImagingDiagnostic Techniques and ProceduresDiagnosisTomographyInvestigative TechniquesAngiographyDiagnostic Techniques, CardiovascularDiagnostic Techniques, Ophthalmological

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 7, 2015

First Posted

March 23, 2016

Study Start

July 1, 2015

Primary Completion

December 1, 2017

Study Completion

January 1, 2018

Last Updated

September 14, 2020

Record last verified: 2020-09

Data Sharing

IPD Sharing
Will not share

Locations

AU(1)