1\) Policy change affecting C\&Cs; 2) interm analysis revealing overt differences
PSVCC
Comparing Health & Social Outcomes Between Opioid-Dependent Individuals in Compulsory Drug Rehabilitation Centers and Voluntary Drug Treatment Clinics in Klang Valley, Malaysia
Sponsor study identifier
Secondary identifiers
NIH
NIH
NIH
OTHER · Malaysian Ministry of Education (High Impact Research Grant)
observational
281
0 countries
N/A
Study Start
August 2012
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
September 2015
Actual (reported)Study Completion
September 2015
Actual (reported)This observational study compares the health and social outcomes between opioid-dependent individuals who are either recently released from a compulsory drug detention center (CDDC) or recently discharged from a voluntary treatment center (VTC) providing methadone maintenance therapy, in Malaysia.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
September 2015
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
August 2012
Date type not reportedThis date has not been verified as actual or estimated.
September 2015
Actual (reported)September 2015
Actual (reported)February 16, 2016
Actual (reported)March 3, 2016
Actual (reported)Occurrence of opioid use (urine-toxicology)
Year following release from CDDC or discharge from VTC
Occurrence of any drug use (urine-toxicology)
Year following release from CDDC or discharge from VTC
Occurrence of amphetamine use (urine-toxicology)
Year following release from CDDC or discharge from VTC
Occurrence of benzodiazepine use (urine-toxicology)
Year following release from CDDC or discharge from VTC
Occurrence of methadone use (urine-toxicology)
Year following release from CDDC or discharge from VTC
Occurrence of buprenorphine use (urine-toxicology)
Year following release from CDDC or discharge from VTC
Occurrence of drug or methadone use (self-report)
Year following release from CDDC or discharge from VTC
Addiction Severity (self-report)
Compared at 3, 6, 9 and 12-months following release from CDDC or discharge from VTC
Occurrence of non-fatal overdose (self-report)
Year following release from CDDC or discharge from VTC
Conventional drug treatment in Malaysia and Southeast Asia including detention for an average of 2 years, including educational and job skills programs and physical education. Medical therapies for treating substance use disorders, such as opioid-agonist treatment (OAT), are unavailable.
Voluntary drug treatment facilities, called 'Cure and Care' centers in Malaysia, that provide methadone maintenance therapy in addition to psychosocial interventions, recreational programming, and vocational training, among other activities.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
The study will be conducted among opioid-dependent individuals initiating MMT in C\&C Centers and opioid-dependent individuals being released from Pusat Serenti who consent to participating in the study.
Wegman MP, Altice FL, Kaur S, Rajandaran V, Osornprasop S, Wilson D, Wilson DP, Kamarulzaman A. Relapse to opioid use in opioid-dependent individuals released from compulsory drug detention centres compared with those from voluntary methadone treatment centres in Malaysia: a two-arm, prospective observational study. Lancet Glob Health. 2017 Feb;5(2):e198-e207. doi: 10.1016/S2214-109X(16)30303-5. Epub 2016 Dec 8.
Frederick Altice, MD
Yale University
Adeeba Kamarulzaman, FRACP
University of Malaya
281 participants (actual enrollment reported by the registry).
First Submitted
February 16, 2016
First Posted
March 3, 2016
Study Start
August 2012
Date type not reportedThis date has not been verified as actual or estimated.
Opiate Detoxification Using the Combined Hemoperfusion-hemodialysis
Contact the study team to confirm eligibility.
Primary Completion
September 2015
Actual (reported)Study Completion
September 2015
Actual (reported)Last Updated
March 3, 2016
Record last verified: 2016-02
See links at end of this record for accessing de-identified data and documentation.
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: