NCT02690402

Brief Summary

Older people are a very heterogeneous population characterized by a high interindividual variability. Functional abilities (walking, transfers ...) used to classify individuals aged (Lalive d'épinay et al., 1999) in three categories: independent, frail and dependent (HAS, 2005). Frailty is generally considered as a state that precedes dependent status and, unlike the latter, is still reversible (Fried et al., 2001). Now, it's necessary to understand and quantify the indicators above the dependence of the elderly from a multidisciplinary approach to frailty, is a critical public health issue for developing non-drug therapeutic interventions adapted to delay the institutionalization. Through this study, it is to identify risk and protective factors of frailty and their relationships with physical activity, evaluate them and propose an appropriate care to the patient. This study should enable the production of new scientific knowledge to improve the health and quality of life of older people.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
970

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2016

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 5, 2015

Completed
5 months until next milestone

First Posted

Study publicly available on registry

February 24, 2016

Completed
7 months until next milestone

Study Start

First participant enrolled

September 12, 2016

Completed
5.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 24, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 24, 2022

Completed
Last Updated

March 24, 2026

Status Verified

March 1, 2026

Enrollment Period

5.4 years

First QC Date

October 5, 2015

Last Update Submit

March 20, 2026

Conditions

Fragility

Outcome Measures

Primary Outcomes (3)

  • Gait analysis

    change from baseline physical activity at 3 months

  • Isocinetic evaluation

    change from baseline physical activity at 3 months

  • Questionnaire : Physical activity, psychometric

    change from baseline physical activity at 3 months

Study Arms (1)

adapted physical activity

EXPERIMENTAL

a personalized care will be offered in terms of adapted physical activity

Behavioral: adapted physical activity

Interventions

adapted physical activityBEHAVIORAL

The study begins with an evaluation of physical strenght and cognitive and psychometric assessment.Then, a personalized care will be offered in terms of adapted physical activity. The evaluation protocol will be performed again to measure the impact of physical activity three months after the first assessment.

adapted physical activity

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersYes
Age GroupsOlder Adult (65+)

You may qualify if:

  • Patient who signed the informed consent
  • Older men and women ≥ 65 years
  • Can walk without technical help

You may not qualify if:

  • Patient with protective measures (guardianship, curatorship, and deprivation of liberty).
  • Patient with a neurological problem
  • No affiliation to a social security scheme (beneficiary or assignee)
  • Knee and / or hip prosthesis
  • Orthopedic complications with repercussions on walking activities

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU de Nice

Nice, 06000, France

Location

Related Publications (4)

  • Piche E, Gerus P, Chorin F, Jaafar A, Guerin O, Zory R. The effect of different dual tasks conditions on gait kinematics and spatio-temporal walking parameters in older adults. Gait Posture. 2022 Jun;95:63-69. doi: 10.1016/j.gaitpost.2022.04.006. Epub 2022 Apr 12.

    PMID: 35453085BACKGROUND

  • Deshayes M, Corrion K, Zory R, Guerin O, Chorin F, d'Arripe-Longueville F. Relationship between personality and physical capacities in older adults: The mediating role of subjective age, aging attitudes and physical self-perceptions. Arch Gerontol Geriatr. 2021 Jul-Aug;95:104417. doi: 10.1016/j.archger.2021.104417. Epub 2021 Apr 8.

    PMID: 33882421BACKGROUND

  • Piche E, Chorin F, Gerus P, Jaafar A, Reneaud N, Guerin O, Zory R. Validity of a simple sit-to-stand method for assessing force-velocity profile in older adults. Exp Gerontol. 2021 Dec;156:111595. doi: 10.1016/j.exger.2021.111595. Epub 2021 Oct 19.

    PMID: 34673170BACKGROUND

  • Roche N, Chorin F, Gerus P, Deshayes M, Guerin O, Zory R. Effects of age, gender, frailty and falls on spatiotemporal gait parameters: a retrospective cohort study. Eur J Phys Rehabil Med. 2021 Dec;57(6):923-930. doi: 10.23736/S1973-9087.21.06831-3. Epub 2021 May 18.

    PMID: 34002975RESULT

Study Officials

  • Olivier GUERIN, PhD

    Centre Hospitalier Universitaire de Nice

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 5, 2015

First Posted

February 24, 2016

Study Start

September 12, 2016

Primary Completion

January 24, 2022

Study Completion

January 24, 2022

Last Updated

March 24, 2026

Record last verified: 2026-03

Locations

FR(1)