Three Different Oral Hygiene Regimes on Three Volatile Sulfur Compounds

NCT02689297 | Completed Phase 4

• 1 other identifier: OHP-018-EI-2
• Study Type: interventional
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of the study is to evaluate the effect of various oral hygiene regimes on three volatile sulfur compounds.

Conditions

Halitosis

Outcome Measures

Primary Outcomes (1)

• Three different volatile sulfur compounds

  Investigator measured three different volatile sulfur compounds: hydrogen sulfide, methyl mercaptan, dimethyl sulfide concentrations (ng/10ml) by using Oral chroma.

  up to 5weeks

Secondary Outcomes (4)

• Oral Health examination

  up to 5weeks

• Tongue coating characteristics

  up to 5weeks

• Number of teeth with bleeding on probing

  up to 5weeks

• Plaque index score

  up to 5weeks

Study Arms (2)

group A

OTHER

Mouthwash (chlorine dioxide 12ml two times per day, for three weeks)

Other: chlorine dioxide

group B

OTHER

Small toothbrush for tongue cleaning two times per day for three weeks

Other: small toothbrush for tongue cleaning

Interventions

chlorine dioxide OTHER

First week, subjects were instructed to do regular tooth brushing. After that group A was requested to use chlorine dioxide mouthwash two time per days for three weeks in addition to tooth brushing and then, one week for combination of tooth brushing, tongue cleaning and mouth washing.

group A

small toothbrush for tongue cleaning OTHER

First week, subjects were instructed to do regular tooth brushing. After that group B was requested to brush their tongue with small toothbrush two time per days for three weeks in addition to tooth brushing and then, one week for combination of tooth brushing, tongue cleaning and mouth washing.

group B

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Clinical diagnosis of oral malodor
• No systemic diseases and no severe dental diseases
• At least 20 functional teeth

You may not qualify if:

• Risky oral habit (smoking and betel quid chewing)
• Current use of antibiotics or any drugs
• Current use of any kind of mouthwash

Sponsors & Collaborators

• Tokyo Medical and Dental University: lead

MeSH Terms

Conditions

Halitosis

Interventions

chlorine dioxide

Condition Hierarchy (Ancestors)

Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: phase 4
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Graduate student, Department of Oral Health Promotion

Study Record Dates

• First Submitted: February 8, 2016
• First Posted: February 23, 2016
• Study Start: September 1, 2013
• Primary Completion: October 1, 2013
• Study Completion: November 1, 2013
• Last Updated: February 23, 2016

Record last verified: 2016-02