NCT02674113

Brief Summary

The purpose of this research is to determine differences in outcomes in patients who receive regional anesthesia (a fascia iliaca block) versus placebo prior to undergoing hip arthroscopy with labral repair and/or debridement and osteoplasty for hip impingement.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Oct 2015

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2015

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

November 7, 2015

Completed
3 months until next milestone

First Posted

Study publicly available on registry

February 4, 2016

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2017

Completed
Last Updated

February 10, 2017

Status Verified

February 1, 2017

Enrollment Period

2 years

First QC Date

November 7, 2015

Last Update Submit

February 9, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Subject log to record number of pain pills taken by subject for 7 days

    A log that is used by the subject to record how many oral pain medications they take for 7 days.

    7 days

Secondary Outcomes (10)

  • Record of Pain Medication given in PACU

    immediately post-op (while in PACU, on average 1-4 hours total)

  • Harris Hip score

    6 weeks

  • Visual analog pain scale

    6 weeks

  • iHOT-12 (international hip outcome tool)

    6 weeks

  • HOOS (hip disability and osteoarthritis outcome score)

    6 weeks

  • +5 more secondary outcomes

Study Arms (2)

regional anesthesia bupivacaine

ACTIVE COMPARATOR

regional anesthesia (a single shot fascia iliaca block using bupivacaine) prior to hip arthroscopy

Drug: regional anesthesia bupivacaine

regional anesthesia placebo

PLACEBO COMPARATOR

subcutaneous injection procedure placebo (0.9% sodium chloride in water)

Drug: regional anesthesia placebo

Interventions

a single shot fascia iliaca block using bupivacaine prior to hip arthroscopy

Also known as: Exparel, Sensorcaine, Marcaine
regional anesthesia bupivacaine

subcutaneous injection procedure using a normal saline placebo (0.9% sodium chloride in water)

Also known as: Sodium Chloride Injection
regional anesthesia placebo

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Patient undergoing primary hip arthroscopy with labral repair and osteoplasty for hip impingement
  • Age 18-45 years old
  • Not pregnant
  • No history of neuropathic pain
  • No radiographic signs of osteoarthritis of the operative hip (Tönnisgrade 1)
  • Willing and able to comply with post-operative hip arthroscopy protocol
  • No documented allergy to anesthetic agents
  • Able to attend follow up appointments

You may not qualify if:

  • Allergy to regional anesthetic
  • Age \<18 or \>45 years
  • Pregnant females
  • History of neuropathic pain
  • Radiographic signs of osteoarthritis (Tönnis grade 2)
  • Unable to speak/understand English
  • Currently imprisoned
  • Unwilling/unable to provide consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Missouri Health System

Columbia, Missouri, 65212, United States

Location

MeSH Terms

Conditions

Femoracetabular Impingement

Interventions

BupivacaineSodium Chloride

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

AnilidesAmidesOrganic ChemicalsAniline CompoundsAminesChloridesHydrochloric AcidChlorine CompoundsInorganic ChemicalsSodium Compounds

Study Officials

  • Ajay Aggarwal, MD

    University of Missouri Health System

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor of Orthopedic Surgery

Study Record Dates

First Submitted

November 7, 2015

First Posted

February 4, 2016

Study Start

October 1, 2015

Primary Completion

October 1, 2017

Study Completion

October 1, 2017

Last Updated

February 10, 2017

Record last verified: 2017-02

Locations