NCT02671292

Brief Summary

To determine whether reducing loss of control eating (LOC) with Interpersonal Psychotherapy-Weight Gain (IPT-WG) will be effective for adolescent military-dependents who report such behavior. The investigators will examine whether IPT-WG influences body weight gain trajectories and prevents worsening disordered eating, psychosocial problems, and metabolic functioning among military dependents at heightened risk for adult obesity and disordered eating. This study will provide key efficacy data for a new promising obesity prevention program for youth from military families.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for not_applicable obesity

Timeline
Completed

Started Jul 2015

Longer than P75 for not_applicable obesity

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2015

Completed
8 days until next milestone

First Submitted

Initial submission to the registry

July 9, 2015

Completed
7 months until next milestone

First Posted

Study publicly available on registry

February 2, 2016

Completed
5.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2021

Completed
Last Updated

February 26, 2019

Status Verified

February 1, 2019

Enrollment Period

5.8 years

First QC Date

July 9, 2015

Last Update Submit

February 23, 2019

Conditions

Keywords

Loss of Control EatingBinge EatingObesityPreventionInterpersonal PsychotherapyAdolescent

Outcome Measures

Primary Outcomes (1)

  • Participant Weight

    Weight will be measured

    Change in weight from baseline to 3 years post-treatment

Secondary Outcomes (9)

  • Presence of binge eating

    Change in presence of binge eating from baseline to 1 year post-treatment

  • Waist Circumference

    Change in waist circumference from baseline to 3 years post-treatment

  • Blood Pressure

    Change in blood pressure from baseline to 3 years post-treatment

  • Triglycerides

    Change in triglycerides from baseline to 3 years post-treatment

  • HDL Cholesterol

    Change in HDL cholesterol from baseline to 3 years post-treatment

  • +4 more secondary outcomes

Study Arms (2)

Interpersonal Psychotherapy (IPT-WG)

EXPERIMENTAL

IPT-WG targets the difficult social functioning and stressful events that are associated with loss of control eating and that are highly relevant to the adolescent children of military personnel.

Behavioral: Interpersonal Psychotherapy

Health Education (HE)

ACTIVE COMPARATOR

HE improves knowledge on various health topics including, alcohol, drug and tobacco use, depression and suicide, nutrition and body image, nonviolent conflict resolution, sun safety, exercise, and domestic violence.

Other: Health Education

Interventions

IPT-WG involves one initial 1.5-hour individual session, and 12 weekly 90-minute group sessions. The IPT-WG group sessions follow 3 phases (initial, middle, and termination) and use the interpersonal inventory to identify interpersonal problems that might be contributing to or exacerbated by LOC eating. A framework of common problem areas is used to teach interpersonal problem-solving and communication skills and educate youth about risk factors for excessive weight gain and warning signs such as eating in response to negative affect as opposed to hunger, or feeling a sense of LOC while eating.

Interpersonal Psychotherapy (IPT-WG)

The HE group is based upon the "HEY-Durham" health program designed by researchers at Duke University. This program, designed to be delivered to youth attending community high schools, was adapted to a 12-week program (each session is 90 minutes). Additionally, individuals will attend a pre-group individual meeting with the group leaders to review family health history.The curriculum includes focus on various health topics, including alcohol, drug and tobacco use, depression and suicide, nutrition and body image, nonviolent conflict resolution, sun safety, exercise, and domestic violence. Session content will be largely identical for boys and girls, with the exception of gender-specific videos and articles (e.g., on body image), which will be tailored for each sex.

Health Education (HE)

Eligibility Criteria

Age12 Years - 17 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Age between 12 and 17 years (at the start of the study)
  • BMI at or above the 85th percentile for age and sex
  • English-speaking
  • Ability to complete study procedures, including the ability to participate in a group
  • \> 1 episode of LOC eating during the 3 months prior to assessment
  • Must have a parent(s) enrolled in TRICARE at the time of study initiation
  • The consenting parent or caregiver must be able to comprehend English.

You may not qualify if:

  • Presence of a chronic major medical illness: renal, hepatic, gastrointestinal, endocrinologic (e.g., Cushing syndrome, hyper- or hypothyroidism), hematological problems or pulmonary disorders (other than asthma not requiring continuous medication).
  • Presence of a documented, obesity-related medical complication that would require a more aggressive weight loss intervention approach: type 2 diabetes, hyperlipidemia, hypertension, fasting hyperglycemia, or nonalcoholic steatohepatitis.
  • Self-reported current pregnancy, current breast-feeding, or recently pregnant girls (within 1 year of delivery).
  • Current, regular use of prescription medications that affect appetite, mood, or body weight: currently prescribed SSRI's, neuroleptics, tricyclics, stimulants, or any other medication known to affect appetite, mood, or body weight. For girls, oral contraceptive use will be permitted, provided the contraceptive has been used for at least two months before starting the prevention groups. Medication use for non-serious conditions (e.g., acne) will be considered on a case-by-case basis.
  • Current involvement in psychotherapy or a structured weight loss program.
  • Weight loss during the past two months for any reason exceeding 3% of body weight.
  • Current anorexia nervosa or bulimia nervosa as determined by documented medical history or if uncovered during K-SADS semi-structured interview. Current binge eating disorder (BED) will be permitted, although adolescents will be informed that they have an eating disorder and have the option to participate in the study or seek outside treatment (and not participate in the study).
  • Individuals who have major depressive disorder, psychoses, current substance or alcohol abuse, conduct disorder, as determined by Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS) semi-structured interview and as defined by criteria outlined in the DSM-5, or any other DSM psychiatric disorder that, in the opinion of the investigators, would impede competence or compliance or possibly hinder completion of the study.
  • \. None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Uniformed Services University of the Health Sciences

Bethesda, Maryland, 20814, United States

RECRUITING

Fort Belvoir Community Hospital

Fort Belvoir, Virginia, 22060, United States

RECRUITING

Related Publications (1)

  • Solomon S, Shank LM, Lavender JM, Neyland MKH, Gallager-Teske J, Markos B, Haynes H, Repke H, Rice AJ, Sbrocco T, Wilfley DE, Schvey NA, Jorgensen S, Ford B, Ford CB, Haigney M, Klein DA, Quinlan J, Tanofsky-Kraff M. The Relationship Between Anxiety, Coping, and Disordered-Eating Attitudes in Adolescent Military-Dependents at High-Risk for Excess Weight Gain. Mil Psychol. 2023;35(2):95-106. doi: 10.1080/08995605.2022.2083448. Epub 2022 Jun 21.

MeSH Terms

Conditions

ObesityOverweightBulimia

Interventions

Interpersonal Psychotherapy

Condition Hierarchy (Ancestors)

OvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsHyperphagiaSigns and Symptoms, Digestive

Intervention Hierarchy (Ancestors)

PsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Marian Tanofsky-Kraff, Ph.D.

    Uniformed Services University of the Health Sciences

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Mary Quattlebaum, B.A.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 9, 2015

First Posted

February 2, 2016

Study Start

July 1, 2015

Primary Completion

May 1, 2021

Study Completion

May 1, 2021

Last Updated

February 26, 2019

Record last verified: 2019-02

Data Sharing

IPD Sharing
Will not share

Locations