NCT02667509

Brief Summary

Myopia has emerged as a major health issue in east Asia, because of its increasingly high prevalence in the past few decades (now 80-90% in school-leavers), and because of the sight-threatening pathologies associated with high myopia, which now aff ects 10-20% of those completing secondary schooling in this part of the world. Similar, but less marked, changes are occurring in other parts of the world. The higher prevalence of myopia in east Asian cities seems to be associated with increasing educational pressures, combined with life-style changes, which have reduced the time children spend outside.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
852,441

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2005

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2005

Completed
10.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2015

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

January 24, 2016

Completed
5 days until next milestone

First Posted

Study publicly available on registry

January 29, 2016

Completed
Last Updated

April 14, 2016

Status Verified

April 1, 2016

Enrollment Period

10.8 years

First QC Date

January 24, 2016

Last Update Submit

April 12, 2016

Conditions

Refractive Error

Keywords

Evolutionary Model

Outcome Measures

Primary Outcomes (1)

  • Refractive error of both eyes measured by autorefractor and subjective measuring

    Baseline

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Subjects from all the province of China who undergoing the examination of Refractive error from 2005 to 2015 year.

You may qualify if:

  • Patients complete the examination of Refractive error from 2005 to 2015 year.

You may not qualify if:

  • Patients could not complete the examination of Refractive error

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Zhongshan Ophthalmic Center, Sun Yat-sen University

Guangzhou, Guangdong, 510060, China

Location

Related Publications (1)

  • Morgan IG, Ohno-Matsui K, Saw SM. Myopia. Lancet. 2012 May 5;379(9827):1739-48. doi: 10.1016/S0140-6736(12)60272-4.

    PMID: 22559900BACKGROUND

Related Links

MeSH Terms

Conditions

Refractive Errors

Condition Hierarchy (Ancestors)

Eye Diseases

Study Officials

  • Haotian Lin Lin, M.D., Ph.D

    Zhongshan Ophthalmic Center, Sun Yat-sen University

    STUDY DIRECTOR

  • Yizhi Liu, M.D., Ph.D

    Zhongshan Ophthalmic Center, Sun Yat-sen University

    STUDY CHAIR

  • Erping Long, M.D., Ph.D

    Zhongshan Ophthalmic Center, Sun Yat-sen University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator, Home for Cataract Children, Zhongshan Ophthalmic Center

Study Record Dates

First Submitted

January 24, 2016

First Posted

January 29, 2016

Study Start

January 1, 2005

Primary Completion

October 1, 2015

Study Completion

October 1, 2015

Last Updated

April 14, 2016

Record last verified: 2016-04

Locations

CN(1)