NCT02665208

Brief Summary

The primary purpose of this study is to understand the feasibility of a text messaging intervention developed by the National Cancer Institute, known as Smokefreetxt, to improve smoking cessation among opiate and/or alcohol dependent participants discharged from an inpatient detoxification unit and enrolled in an office-based buprenorphine program patients (OBBP). Participants will be randomized to 1) treatment as usual (TAU) comprised of informational pamphlets and information for a 1800 quit line; and a prescription for a nicotine replacement therapy (NRT) (i.e. nicotine replacement patches based on the quantity of baseline self-reported smoking, or nicotine replacement gum (2mg) #10, for 28 days which is offered routinely to all inpatients at Bellevue at the time of discharge) versus the SmokeFreeTXT intervention plus prescriptions for NRT.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
203

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2015

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2015

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2015

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

January 20, 2016

Completed
7 days until next milestone

First Posted

Study publicly available on registry

January 27, 2016

Completed
1.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2017

Completed
Last Updated

December 6, 2017

Status Verified

December 1, 2017

Enrollment Period

6 months

First QC Date

January 20, 2016

Last Update Submit

December 4, 2017

Conditions

Keywords

cigarettessmokingopiate-dependencealcoholdetoxification

Outcome Measures

Primary Outcomes (3)

  • Difference in patient acceptability assessed via rates of participant adoption of TMI

    24 Weeks

  • Feasibility measured by rates of retention in the TMI

    24 Weeks

  • Clinical impact assessed using self-reported abstinence at week 1 via a text message inquiry from study

    24 Weeks

Secondary Outcomes (1)

  • Change in pattern of mobile device, computer, and internet usage.

    24 Weeks

Study Arms (3)

Treatment As Usual (TAU)

ACTIVE COMPARATOR

Participants will receive informational pamphlets and information for a 1800 quit line, and a prescription for a nicotine replacement therapy (NRT) for 7 Days

Other: Treatment As Usual (TAU)

Nicotine Replacement Therapies

ACTIVE COMPARATOR

Participants will receive a prescription for a nicotine replacement therapy (NRT) for 7 Days.

Drug: Nicotine Replacement Therapies

Text Message Intervention

ACTIVE COMPARATOR

Participants will receive up to 5 messages a day with message content informed by principles of cognitive behavioral therapy using software developed and maintained by the National Cancer Institute.

Behavioral: Text Message Intervention (TMI)

Interventions

informational pamphlets and information from 1800 quit line + prescription for nicotine replacement therapy (NRT) based on on the quantity of baseline self-reported smoking, or nicotine replacement gum (2mg)

Treatment As Usual (TAU)

a prescription for a nicotine replacement therapy (NRT) (i.e. nicotine replacement patches based on the quantity of baseline self-reported smoking, or nicotine replacement gum (2mg)

Nicotine Replacement Therapies
Text Message Intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • self-described every or some day smoker
  • diagnosed with opiate dependence and/or alcohol dependence (DSM-IV) per Physician medical records (MISYS)
  • Fluency in English and able to provide a written informed consent
  • Currently owning a mobile phone with a working phone number
  • Expected to reside in the New York City area for the next 12 months
  • Understands and able to respond to the intervention text message

You may not qualify if:

  • inability to read or understand English
  • currently using nicotine replacement therapies (patch, gum, e-cigarettes), pharmacotherapy for smoking cessation such as bupropion (zyban, wellbutrin), varenicline (Chantix).
  • suicidal or homicidal ideations
  • any ongoing psychotic disorder, life-threatening medical or psychiatric condition
  • leaves the inpatient detoxification unit prior to completing study enrollment
  • is pregnant, nursing or planning to conceive within the duration of the study period

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

New York University School of Medicine

New York, New York, 10016, United States

Location

MeSH Terms

Conditions

Smoking CessationSmokingOpioid-Related Disorders

Interventions

TherapeuticsNicotine Replacement Therapy

Condition Hierarchy (Ancestors)

Health BehaviorBehaviorNarcotic-Related DisordersSubstance-Related DisordersChemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Drug Therapy

Study Officials

  • Babak Tofighi, MD

    New York University Medical School

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 20, 2016

First Posted

January 27, 2016

Study Start

March 1, 2015

Primary Completion

September 1, 2015

Study Completion

September 1, 2017

Last Updated

December 6, 2017

Record last verified: 2017-12

Locations