NCT02453659

Brief Summary

The long-term goal of this program of research is to develop and disseminate an efficacious, group-based distress tolerance treatment for weight concern (DT-W) that will significantly increase smoking cessation rates among women. The objective of this project is to conduct a preliminary randomized controlled trial (RCT) (N = 60) comparing DT-W to a Health Education (HE) comparison intervention, in which both groups also receive standard behavioral smoking cessation treatment (ST) including counseling and transdermal nicotine patch (TNP), and examine potential mechanisms that may underlie the efficacy of DT-W in improving smoking outcomes at 1-, 3-, and 6-month follow-ups.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started May 2015

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2015

Completed
20 days until next milestone

First Submitted

Initial submission to the registry

May 21, 2015

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 25, 2015

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2018

Completed
Last Updated

March 28, 2019

Status Verified

March 1, 2019

Enrollment Period

3.6 years

First QC Date

May 21, 2015

Last Update Submit

March 26, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Point prevalence abstinence from smoking: percentage of participants in each treatment group who report abstinence from smoking for the 7 days prior to each follow-up assessment

    The investigators will compare the percentage of participants in each treatment group who report abstinence from smoking for the 7 days prior to each follow-up assessment (1-, 3-, and 6-months post-quit date).

    6 months post-quit date

Study Arms (2)

Distress Tolerance Treatment for Weight Concern (DT-W)

EXPERIMENTAL

DT-W is delivered over a 9 week period with 1 1-hr individual session during week 1, 8 weekly 1.5-hr group counseling sessions during weeks 2-9, and 1 20-minute individual telephone session during week 4. Session content includes distress tolerance intervention for weight concern plus standard behavioral smoking cessation treatment. Participants also receive 8 weeks of nicotine patch.

Behavioral: Distress Tolerance Treatment for Weight Concern (DT-W)Behavioral: Smoking Cessation counselingDrug: Transdermal Nicotine Patch

Health Education (HE)

ACTIVE COMPARATOR

HE is delivered over a 9 week period with 1 1-hr individual session during week 1, 8 weekly 1.5-hr group counseling sessions during weeks 2-9, and 1 20-minute individual telephone session during week 4. Session content includes smoking health education program plus standard behavioral smoking cessation treatment. Participants also receive 8 weeks of nicotine patch.

Behavioral: Health Education (HE)Behavioral: Smoking Cessation counselingDrug: Transdermal Nicotine Patch

Interventions

Distress Tolerance Treatment for Weight Concern (DT-W)
Health Education (HE)
Distress Tolerance Treatment for Weight Concern (DT-W)Health Education (HE)
Distress Tolerance Treatment for Weight Concern (DT-W)Health Education (HE)

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • female
  • at least 18 years of age
  • smoke 5 or more cigarettes per day
  • daily smoker for at least the past year
  • report motivation to quit smoking in the next month of at least 5 on a 10 point scale
  • report concern of at least 50 on at least one of two 100 point scales assessing weight concern
  • able to travel to study location for study appointments

You may not qualify if:

  • current use of other smoking cessation or weight loss therapies
  • current use of other tobacco products at least weekly
  • diagnosis or treatment for non-nicotine substance use disorder with substance use during the past 6 months
  • lifetime diagnosis or treatment of eating disorder, bipolar disorder, schizophrenia, or schizoaffective disorder
  • score above established cut-offs on self-report screening measures of depressive symptomology, eating disorder symptomology, alcohol use disorder, or drug use disorder
  • current suicidality or homicidality
  • medical condition that is a contraindication for the use of transdermal nicotine patch
  • lives at same address as current or past participant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Rhode Island Hospital

Providence, Rhode Island, 02903, United States

Location

Related Publications (1)

  • Hartmann-Boyce J, Theodoulou A, Farley A, Hajek P, Lycett D, Jones LL, Kudlek L, Heath L, Hajizadeh A, Schenkels M, Aveyard P. Interventions for preventing weight gain after smoking cessation. Cochrane Database Syst Rev. 2021 Oct 6;10(10):CD006219. doi: 10.1002/14651858.CD006219.pub4.

MeSH Terms

Conditions

Smoking Cessation

Interventions

Tobacco Use Cessation Devices

Condition Hierarchy (Ancestors)

Health BehaviorBehavior

Intervention Hierarchy (Ancestors)

Therapeutics

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 21, 2015

First Posted

May 25, 2015

Study Start

May 1, 2015

Primary Completion

December 1, 2018

Study Completion

December 1, 2018

Last Updated

March 28, 2019

Record last verified: 2019-03

Locations