Cognitive Behavioural Group Therapy Versus Individual Supportive Therapy for the Prevention of Repeat Suicide Attempts

NCT02664701 | Active Not Recruiting DMC

• 2 other identifiers: PHRC-N/2014/MA-012015-A01585-44
• Study Type: interventional
• Target: 240
• Locations: 1 country
• Sites: 9

Brief Summary

The primary objective of this study is to evaluate the efficacy of a program of 6 sessions of Cognitive Behavioural Group Therapy (CBGT) (as compared to 6 sessions of Individual Supportive Therapy (IST)) designed for preventing repeat suicide attempts at 12 months post-psychotherapy in adults admitted to inpatient care for suicide attempts.

Conditions

Suicidal Ideation; Suicide, Attempt

Outcome Measures

Primary Outcomes (1)

• The primary clinical endpoint is the duration (in days) of a suicide reattempt-free follow-up period

  12 months

Secondary Outcomes (39)

• The Columbia suicide severity rating scale (C-SSRS)

  baseline

• The Columbia suicide severity rating scale (C-SSRS)

  in the 10 days after the end of psychotherapy

• The Columbia suicide severity rating scale (C-SSRS)

  3 months

• The Columbia suicide severity rating scale (C-SSRS)

  6 months

• The Columbia suicide severity rating scale (C-SSRS)

  9 months

Study Arms (2)

Individual supportive therapy

ACTIVE COMPARATOR

Patients randomized to this arm will have individual supportive therapy. Intervention: Baseline evaluation with a psychiatrist Intervention: Individual supportive therapy Intervention: Evaluations with a psychiatrist

Other: Baseline evaluation with a psychiatrist; Other: Individual supportive therapy; Other: Evaluations with a psychiatrist

Cognitive behavioural group therapy

EXPERIMENTAL

Patients randomized to this arm will have cognitive behavioural therapy. Intervention: Baseline evaluation with a psychiatrist Intervention: Cognitive behavioural group therapy Intervention: Evaluations with a psychiatrist

Other: Baseline evaluation with a psychiatrist; Other: Cognitive behavioural group therapy; Other: Evaluations with a psychiatrist

Interventions

Baseline evaluation with a psychiatrist OTHER

Baseline data and questionnaires are established.

Cognitive behavioural group therapy; Individual supportive therapy

Individual supportive therapy OTHER

6 sessions of individual supportive therapy with a psychologist, 1 session per week for 6 weeks

Individual supportive therapy

Cognitive behavioural group therapy OTHER

6 sessions of cognitive behavioural group therapy with a psychologist, 1 session per week for 6 weeks

Cognitive behavioural group therapy

Evaluations with a psychiatrist OTHER

Evaluation withs a psychiatrist in the 10 days following the end of psychotherapy, then at 3, 6, 9, and 12 months.

Cognitive behavioural group therapy; Individual supportive therapy

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• The patient has been correctly informed
• The patient must have given his/her informed and signed consent
• The patient must be insured or beneficiary of a health insurance plan
• French speaking adults (18 years or older) freely hospitalized (in centres or via emergency services) for prevention of suicide and who have a medium or high suicide risk score according to a Mini International Neuropsychiatric Interview structured interview
• Presence of suicidal ideation according to the Beck Suicide Ideation Scale (score \> 3)
• Prior (or recent) suicide attempt within the last three month
• The patient is able to understand the study and capable of giving his/her informed consent
• The patient is available during the weekly time slots proposed by the investigator

You may not qualify if:

• The patient is participating in another study that may interfere with the results or conclusions of this study
• Within the past three months, the patient has participated in another study that may interfere with the results or conclusions of this study
• The patient is under judicial protection, or is an adult under guardianship
• The patient refuses to sign the consent, or it is impossible to correctly inform the patient
• Emergency situations preventing proper study conduct
• History of schizophrenia or other psychotic troubles
• Presence of psychotic symptoms at initial interview
• Serious cognitive impairment
• Medical incapacity to participate

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Nīmes: lead

Study Sites (9)

CHU de Clermont Ferrand - Hôpital Gabriel-Montpied

Clermont-Ferrand, 63003, France

Location

CHU de Lyon - Groupement Hospitalier Edouard Herriot

Lyon, 69437, France

Location

CHRU de Montpellier - Hôpital Lapeyronie

Montpellier, 34295, France

Location

Clinique Les Sophoras

Nîmes, 30000, France

Location

CHRU de Nîmes - Hôpital Universitaire Carémeau

Nîmes, 30029, France

Location

CMME

Paris, 75674, France

Location

CH Henri Laborit

Poitiers, 86021, France

Location

CHRU de Tours - Clinique Psychiatrique Universitaire

Saint-Cyr-sur-Loire, 37540, France

Location

CHRU de Strasbourg - Hôpital Civil

Strasbourg, 67091, France

Location

Related Publications (2)

• Witt KG, Hetrick SE, Rajaram G, Hazell P, Taylor Salisbury TL, Townsend E, Hawton K. Psychosocial interventions for self-harm in adults. Cochrane Database Syst Rev. 2021 Apr 22;4(4):CD013668. doi: 10.1002/14651858.CD013668.pub2.

  PMID: 33884617 DERIVED

• Chaib LS, Lopez-Castroman J, Abbar M. Group Post-Admission Cognitive Therapy for Suicidality vs Individual Supportive Therapy for the prevention of repeat suicide attempts: a randomized controlled trial. Trials. 2020 Oct 27;21(1):889. doi: 10.1186/s13063-020-04816-y.

  PMID: 33109271 DERIVED

MeSH Terms

Conditions

Suicidal Ideation; Suicide, Attempted

Condition Hierarchy (Ancestors)

Suicide; Self-Injurious Behavior; Behavioral Symptoms; Behavior

Study Officials

• Mocrane Abbar, MD

  Centre Hospitalier Universitaire de Nîmes

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 19, 2016
• First Posted: January 27, 2016
• Study Start: October 17, 2017
• Primary Completion: November 1, 2025
• Study Completion: November 1, 2025
• Last Updated: August 20, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

FR (9)