NCT02646488

Brief Summary

The primary purpose of this study is to evaluate the effectiveness of practice facilitation as a quality improvement strategy for implementing the Million Hearts' ABCS treatment guidelines for reducing cardiovascular disease (CVD) among high-risk patients who receive care in primary care practices in New York City. The ABCS refer to the following: Aspirin in high-risk individuals (A), Blood pressure control and management (B), Cholesterol management (C), and Smoking cessation (S). The long-term goal is to create a robust infrastructure to disseminate and implement evidence based practice guidelines (EBPG) findings in primary care practices and improve practices' capacity to receive and implement other EBPG findings in the future.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
276

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2015

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2015

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

December 30, 2015

Completed
6 days until next milestone

First Posted

Study publicly available on registry

January 5, 2016

Completed
3.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2019

Completed
Last Updated

May 20, 2019

Status Verified

May 1, 2019

Enrollment Period

3.7 years

First QC Date

December 30, 2015

Last Update Submit

May 17, 2019

Conditions

Keywords

cholesterolsmokingaspirinchronic care model

Outcome Measures

Primary Outcomes (5)

  • Percentage of patients with documented use of aspirin or other antithrombotic.

    18 Months

  • Percentage of patients who had a diagnosis of hypertension (HTN) and whose blood pressure (BP) was adequately controlled

    18 Months

  • Percentage of patients who had a fasting lipoprotein (LDL) test performed and whose risk-stratified fasting LDL is at or below the recommended low density lipoprotein (LDL) goal

    18 Months

  • Change in the percentage of patients who had a low density lipoprotein (LDL) test who are prescribed a recommended dose of statin based on risk status if indicated.

    18 Months

  • Percentage of patients who were screened about tobacco use one or more times within 24 months AND who received cessation counseling intervention if identified as a tobacco user.

    24 Months

Secondary Outcomes (1)

  • Percentage of patients aged 18 through 85 years of age who had a diagnosis of hypertension (HTN) who are prescribed recommended medications, if indicated.

    18 Months

Study Arms (4)

Cluster 1

ACTIVE COMPARATOR

Consists of 80 sites chosen by block randomization in four waves every three months (80 in the first three waves and 60 in the last wave).

Behavioral: Million Hearts ABCS 6 MonthsBehavioral: Standard Care Regimen 9 MonthsBehavioral: Standard Care Regimen 12 MonthsBehavioral: Standard Care Regimen 15 MonthsBehavioral: Standard Care Regimen 18 MonthsBehavioral: Follow Up Post Intervention 21 MonthsBehavioral: Follow Up Post Intervention 24 Months

Cluster 2

ACTIVE COMPARATOR

Consists of 80 sites chosen by block randomization in four waves every three months (80 in the first three waves and 60 in the last wave).

Behavioral: Million Hearts ABCS 6 MonthsBehavioral: Million Hearts ABCS 9 MonthsBehavioral: Standard Care Regimen 12 MonthsBehavioral: Standard Care Regimen 15 MonthsBehavioral: Standard Care Regimen 18 MonthsBehavioral: Standard Care Regimen 21 MonthsBehavioral: Follow Up Post Intervention 24 MonthsBehavioral: Follow Up Post Intervention 27 Months

Cluster 3

ACTIVE COMPARATOR

Consists of 80 sites chosen by block randomization in four waves every three months (80 in the first three waves and 60 in the last wave).

Behavioral: Million Hearts ABCS 6 MonthsBehavioral: Million Hearts ABCS 9 MonthsBehavioral: Million Hearts ABCS 12 MonthsBehavioral: Standard Care Regimen 15 MonthsBehavioral: Standard Care Regimen 18 MonthsBehavioral: Standard Care Regimen 21 MonthsBehavioral: Standard Care Regimen 24 MonthsBehavioral: Follow Up Post Intervention 27 MonthsBehavioral: Follow Up Post Intervention 30 Months

Cluster 4

ACTIVE COMPARATOR

Consists of 80 sites chosen by block randomization in four waves every three months (80 in the first three waves and 60 in the last wave).

Behavioral: Million Hearts ABCS 6 MonthsBehavioral: Million Hearts ABCS 9 MonthsBehavioral: Million Hearts ABCS 12 MonthsBehavioral: Million Hearts ABCS 15 MonthsBehavioral: Standard Care Regimen 18 MonthsBehavioral: Standard Care Regimen 21 MonthsBehavioral: Standard Care Regimen 24 MonthsBehavioral: Standard Care Regimen 27 MonthsBehavioral: Follow Up Post Intervention 30 MonthsBehavioral: Follow Up Post Intervention 33 Months

Interventions

The ABCS refer to the following: Aspirin in high-risk individuals (A), Blood pressure control and management (B), Cholesterol management (C), and Smoking cessation (S).

Also known as: Chronic Care Model
Cluster 1Cluster 2Cluster 3Cluster 4

The ABCS refer to the following: Aspirin in high-risk individuals (A), Blood pressure control and management (B), Cholesterol management (C), and Smoking cessation (S).

Cluster 2Cluster 3Cluster 4

The ABCS refer to the following: Aspirin in high-risk individuals (A), Blood pressure control and management (B), Cholesterol management (C), and Smoking cessation (S).

Cluster 3Cluster 4

The ABCS refer to the following: Aspirin in high-risk individuals (A), Blood pressure control and management (B), Cholesterol management (C), and Smoking cessation (S).

Cluster 4
Cluster 1Cluster 2
Cluster 1Cluster 2Cluster 3
Cluster 1Cluster 2Cluster 3Cluster 4
Cluster 2Cluster 3Cluster 4
Cluster 3Cluster 4
Cluster 1Cluster 2
Cluster 2Cluster 3
Cluster 3Cluster 4

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Eligibility includes working full or part time at the study site.
  • Steering committee members or other key stakeholder from the following groups: Health Plan Chief Medical Officer, State health officials in the Chronic Disease Program, and leadership from relevant national associations (American Heart Association), members of Advisory Board of CHCANYS (these are physician leaders).
  • at least one of the ABCS risk factors for CVD (i.e., hypertension, hyperlipidemia, eligible for aspirin and/or is a current smoker)
  • must have received care at the clinic for at least 12 months
  • Patients eligible for aspirin are those with a documented ICD-9 code for ischemic vascular disease in the last 12 months. Similarly, patients with a diagnosis of hypertension and/or hyperlipidemia will have a documented ICD-9 code for the targeted risk factor
  • Smokers will be identified by a documented ICD-9 code, prescription for a cessation medication in the last 12 months or documentation in the chart (e.g. meaningful use measure) during the last 12 months (see outcome measures)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

New York University School of Medicine

New York, New York, 10016, United States

Location

Related Publications (5)

  • Gold HT, Siman N, Cuthel AM, Nguyen AM, Pham-Singer H, Berry CA, Shelley DR. A practice facilitation-guided intervention in primary care settings to reduce cardiovascular disease risk: a cost analysis. Implement Sci Commun. 2021 Feb 6;2(1):15. doi: 10.1186/s43058-021-00116-x.

  • Berry CA, Nguyen AM, Cuthel AM, Cleland CM, Siman N, Pham-Singer H, Shelley DR. Measuring Implementation Strategy Fidelity in HealthyHearts NYC: A Complex Intervention Using Practice Facilitation in Primary Care. Am J Med Qual. 2021 Jul-Aug 01;36(4):270-276. doi: 10.1177/1062860620959450.

  • Shelley DR, Gepts T, Siman N, Nguyen AM, Cleland C, Cuthel AM, Rogers ES, Ogedegbe O, Pham-Singer H, Wu W, Berry CA. Cardiovascular Disease Guideline Adherence: An RCT Using Practice Facilitation. Am J Prev Med. 2020 May;58(5):683-690. doi: 10.1016/j.amepre.2019.12.013. Epub 2020 Feb 14.

  • Gepts T, Nguyen AM, Cleland C, Wu W, Pham-Singer H, Shelley D. Accounting for Blood Pressure Seasonality Alters Evaluation of Practice-Level Blood Pressure Control Intervention. Am J Hypertens. 2020 Mar 13;33(3):220-222. doi: 10.1093/ajh/hpz179.

  • Shelley DR, Ogedegbe G, Anane S, Wu WY, Goldfeld K, Gold HT, Kaplan S, Berry C. Testing the use of practice facilitation in a cluster randomized stepped-wedge design trial to improve adherence to cardiovascular disease prevention guidelines: HealthyHearts NYC. Implement Sci. 2016 Jul 4;11(1):88. doi: 10.1186/s13012-016-0450-2.

MeSH Terms

Conditions

Cardiovascular DiseasesHypertensionSmoking

Interventions

Chronic Care Model

Condition Hierarchy (Ancestors)

Vascular DiseasesBehavior

Intervention Hierarchy (Ancestors)

Delivery of Health Care, IntegratedDelivery of Health CarePatient Care ManagementHealth Services Administration

Study Officials

  • Donna Shelley, MD

    New York University Medical School

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 30, 2015

First Posted

January 5, 2016

Study Start

August 1, 2015

Primary Completion

April 1, 2019

Study Completion

April 1, 2019

Last Updated

May 20, 2019

Record last verified: 2019-05

Locations