NCT02631681

Brief Summary

Exercise intervention for men with prostate cancer on androgen deprivation therapy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2014

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2014

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

December 10, 2015

Completed
6 days until next milestone

First Posted

Study publicly available on registry

December 16, 2015

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2017

Completed
Last Updated

August 30, 2019

Status Verified

August 1, 2019

Enrollment Period

3.1 years

First QC Date

December 10, 2015

Last Update Submit

August 28, 2019

Conditions

Outcome Measures

Primary Outcomes (2)

  • Change in 30second Chair-Stand test (30s-CST)

    Test of functional capacity, measured as change

    Baseline, 12 and 24 weeks

  • Change in Graded Cycling Test with Talk Test (GCT-TT)

    Test of functional capacity, measured as change

    Baseline, 12 and 24 weeks

Secondary Outcomes (5)

  • change in QoL

    Baseline, 12 and 24 weeks

  • change in Body composition

    Baseline, 12 and 24 weeks

  • change in Bloodpressure

    Baseline, 12 and 24 weeks

  • Safety of exercise assessed by serious adverse events according to the FDA

    Study period baseline - 24 weeks

  • Compliance assessed by attendance and continued exercise (yes/no)

    Baseline, 12 and 24 weeks

Study Arms (1)

Men with prostate cancer on androgen deprivation therapy

EXPERIMENTAL

Group based supervised combined aerobic and resistance training for 12 weeks.

Behavioral: Group based exercise

Interventions

Supervised group based combined aerobic and resistance training for 12 weeks as part of our normal clinical practice.

Men with prostate cancer on androgen deprivation therapy

Eligibility Criteria

Age18 Years+
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with a prostate cancer diagnosis on androgen deprivation therapy

You may not qualify if:

  • Opioid demanding treatment for skeletal pain
  • Eastern Cooperative Oncology Group performance status \> 2
  • Inability to perform floor and machine exercises independently

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Herlev and Gentofte Hospital

Herlev, Please Select An Option Below, 2100, Denmark

Location

Related Publications (1)

  • Ostergren P, Ragle AM, Jakobsen H, Klausen TW, Vinther A, Sonksen J. Group-based exercise in daily clinical practice to improve physical fitness in men with prostate cancer undergoing androgen deprivation therapy: study protocol. BMJ Open. 2016 Jun 29;6(6):e011460. doi: 10.1136/bmjopen-2016-011460.

MeSH Terms

Conditions

Prostatic Neoplasms

Condition Hierarchy (Ancestors)

Genital Neoplasms, MaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsGenital Diseases, MaleGenital DiseasesUrogenital DiseasesProstatic DiseasesMale Urogenital Diseases

Study Officials

  • Peter B Østergren, MD

    Herlev and Gentofte Hospital, Faculty of Health and Medical Sciences, Copenhagen University, Denmark

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
M.D.

Study Record Dates

First Submitted

December 10, 2015

First Posted

December 16, 2015

Study Start

August 1, 2014

Primary Completion

September 1, 2017

Study Completion

September 1, 2017

Last Updated

August 30, 2019

Record last verified: 2019-08

Data Sharing

IPD Sharing
Will not share

Locations