Paroxysmal Atrial Fibrillation in Patients With Acute Ischemic Stroke

NCT02610803 | Completed

• 1 other identifier: HISPACs
• Study Type: observational
• Target: 863
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to estimate the clinical relevance of monitoring patients with acute ischemic stroke with 48 hours' inpatient cardiac telemetry in relation to evaluate the presence of brief runs of premature atrial complexes and new diagnosed atrial fibrillation. Furthermore to evaluate the prognostic significance of brief runs of premature atrial complexes in relation to develop atrial fibrillation, recurrent stroke/transient ischemic attack and death.

Conditions

Ischemic Stroke; Paroxysmal Atrial Fibrillation; Premature Atrial Complexes

Keywords

stroke; ischemic stroke; recurrent stroke; atrial fibrillation; premature atrial complexes; heart rhythm monitoring; cardiac telemetry

Outcome Measures

Primary Outcomes (1)

• Time to death or recurrent stroke

  Up to 4 years

Secondary Outcomes (4)

• Number of patients diagnosed with atrial fibrillation by 48 hours' continuous inpatient cardiac telemetry

  up to 2 days

• Number of patients diagnosed with runs of premature atrial complexes by 48 hours' continuous cardiac telemetry

  up to 2 days

• Time to develop atrial fibrillation in patients without know atrial fibrillation at admission. Registered in Medical journals and discharge letters.

  Up to 4 years

• Number of patients with atrial fibrillation having oral anticoagulant treatment at discharge. Data will be extracted from the Danish Stroke Registry.

  to the day of discharge (up to 4 weeks)

Study Arms (1)

Patients with ischemic stroke

Patients admitted with ischemic stroke from August 2008 to April 2011 (Retrospectively defined).

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with acute ischemic stroke, admitted to our hospital between August 2008-April 2011

You may qualify if:

• admitted with ischemic stroke from August 2008-April 2011
• Registered in the Danish Stroke Registry

You may not qualify if:

• Hemorrhagic stroke
• No Danish civil registration
• no permanent address in Denmark during follow-up.
• patients with lack of telemetry data

Sponsors & Collaborators

• Odense University Hospital: lead

Study Sites (1)

Department of Medical Research, OUH, Svendborg

Svendborg, Funen, 5700, Denmark

Location

MeSH Terms

Conditions

Ischemic Stroke; Atrial Fibrillation; Atrial Premature Complexes; Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Arrhythmias, Cardiac; Heart Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Cardiac Complexes, Premature; Cardiac Conduction System Disease

Study Officials

• Kristina H Vinther, MD

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Medical Doctor

Study Record Dates

• First Submitted: November 13, 2015
• First Posted: November 20, 2015
• Study Start: September 1, 2014
• Primary Completion: September 1, 2015
• Study Completion: October 1, 2015
• Last Updated: November 20, 2015

Record last verified: 2015-11

Locations

DK (1)