VILMA: Therapeutic Results in Acute Mieloblastic Leukemia in Patients Older Than 60 Years
1 other identifier
observational
3,910
1 country
20
Brief Summary
This is a retrospective study to analyze the therapeutic results and clinical evolution all patients diagnosed with AML and aged ≥ 60años or not candidates for chemotherapy intensive, treated according to the different schemes available, including supportive care or palliative.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jul 2015
Typical duration for all trials
20 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2015
CompletedFirst Submitted
Initial submission to the registry
October 13, 2015
CompletedFirst Posted
Study publicly available on registry
November 17, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 15, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
February 15, 2018
CompletedMay 27, 2020
May 1, 2020
2.6 years
October 13, 2015
May 25, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
Response Rate
The main objective of this study is to retrospectively evaluate the therapeutic results in the LMA in all patients older than 60 years or not candidates for intensive chemotherapy in different stages of the disease, regardless of the treatment received, and even if they do not have received (support or palliative treatment, exclusively
8 months
Interventions
Eligibility Criteria
Patients aged ≥60 years, diagnosed of AML or not candidates to intensive chemotherapy
You may qualify if:
- Patients aged ≥60 years, diagnosed of AML or not candidates to intensive chemotherapy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (20)
Hospital General Universitario de Alicante
Alicante, Spain
ICO-Hospital Germans Trias i Pujol
Badalona, Spain
Hospital General Universitari de Castelló
Castelló, Spain
Hospital San Pedro Alcántara
Cáceres, Spain
Hospital Universitario Reina Sofía
Córdoba, Spain
Hospital Universitario de Gran Canaria Doctor Negrín
Las Palmas, Spain
Hospital Lucus Augusti
Lugo, Spain
CIBERONC, Instituto Carlos III
Madrid, Spain
Hospital Clínico San Carlos
Madrid, Spain
Hospital General Universitario Gregorio Marañón
Madrid, Spain
Hospital Univeristario Ramón y Cajal
Madrid, Spain
Hospital Universitario 12 de Octubre, Complutense University, i+12, CNIO
Madrid, Spain
Hospital Universitario Fundación Jiménez Díaz
Madrid, Spain
Hospital General Universitario Morales Meseguer
Murcia, Spain
Hospital Universitario Central de Asturias
Oviedo, Spain
Hospital Universitario Marqués de Valdecilla
Santander, Spain
Hospital Universitario Virgen del Rocío, Instituto de Biomedicina
Seville, Spain
Hospital Clínico Universitario, INCLIVA Biomedical Research Institute
Valencia, Spain
Hospital General Universitario de Valencia
Valencia, Spain
Hospital Universitari i Politècnic La Fe
Valencia, Spain
Related Publications (1)
Martinez-Cuadron D, Serrano J, Gil C, Tormo M, Martinez-Sanchez P, Perez-Simon JA, Garcia-Boyero R, Rodriguez-Medina C, Lopez-Pavia M, Benavente C, Bergua J, Lavilla-Rubira E, Amigo ML, Herrera P, Alonso-Dominguez JM, Bernal T, Colorado M, Sayas MJ, Algarra L, Vidriales MB, Rodriguez-Macias G, Vives S, Perez-Encinas MM, Lopez A, Noriega V, Garcia-Fortes M, Ramos F, Rodriguez-Gutierrez JI, Costilla-Barriga L, Labrador J, Boluda B, Rodriguez-Veiga R, Martinez-Lopez J, Sanz MA, Montesinos P. Evolving treatment patterns and outcomes in older patients (>/=60 years) with AML: changing everything to change nothing? Leukemia. 2021 Jun;35(6):1571-1585. doi: 10.1038/s41375-020-01058-4. Epub 2020 Oct 19.
PMID: 33077867DERIVED
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 13, 2015
First Posted
November 17, 2015
Study Start
July 1, 2015
Primary Completion
February 15, 2018
Study Completion
February 15, 2018
Last Updated
May 27, 2020
Record last verified: 2020-05