Key Insights

Highlights

Success Rate

77% trial completion

Published Results

25 trials with published results (13%)

Research Maturity

72 completed trials (37% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

11.2%

22 terminated out of 197 trials

Success Rate

76.6%

-9.9% vs benchmark

Late-Stage Pipeline

6%

12 trials in Phase 3/4

Results Transparency

35%

25 of 72 completed with results

Key Signals

25 with results77% success22 terminated

Data Visualizations

Phase Distribution

170Total
Not Applicable (22)
Early P 1 (5)
P 1 (82)
P 2 (49)
P 3 (11)
P 4 (1)

Trial Status

Completed72
Recruiting42
Unknown29
Terminated22
Withdrawn10
Not Yet Recruiting10

Trial Success Rate

76.6%

Benchmark: 86.5%

Based on 72 completed trials

Clinical Trials (197)

Showing 20 of 20 trials
NCT07490288Not ApplicableRecruitingPrimary

Venetoclax, Azacitidine and Liposomal Mitoxantrone for Newly Diagnosed AML

NCT06131801Recruiting

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

NCT07508982Phase 1RecruitingPrimary

Phase1b/2 Trial Of AZA + APG1252 In Patients With High-Risk AML

NCT07617285Phase 1RecruitingPrimary

Allogeneic CAR-T(CT0890B) in NKG2DL+ R/R AML

NCT05285813Phase 2TerminatedPrimary

A Phase II Study of Vibecotamab (XmAb14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure

NCT06973668Phase 2RecruitingPrimary

A Randomized Study to Compare Post-transplant Cyclophosphamide, Sirolimus, Ruxolitinib and Post-transplant Cyclophosphamide, Sirolimus, Mycophenolate Mofetil to Prevent Graft Versus Host Disease

NCT06664879Phase 1Active Not RecruitingPrimary

ALLG AMLM26 INTERCEPT (Investigating Novel Therapy to Target Early Relapse and Clonal Evolution as Pre-emptive Therapy in AML): A Multi-arm, Precision-based, Recursive, Platform Trial

NCT07587944RecruitingPrimary

Biomarkers in Bone Marrow Supernatant for Predicting AML Chemosensitivity

NCT06561880Phase 1Recruiting

The Efficacy of Triple Regimen in Newly Diagnosed AML Patients With FLT3 Mutation

NCT06611839Phase 1RecruitingPrimary

Venetoclax in Combination With Ivosidenib and Azacitidine for Newly Diagnosed IDH1-Mutated AML

NCT06744556Phase 2Active Not RecruitingPrimary

HAV Versus DAV/IAV Induction Regimen in Elderly Patients With AML

NCT04977180Phase 2RecruitingPrimary

Cardioprotection in AML

NCT06158828Phase 1Recruiting

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML

NCT03050268Recruiting

Familial Investigations of Childhood Cancer Predisposition

NCT07539818Phase 3Not Yet RecruitingPrimary

Azacitidine + Venetoclax VS Azacitidineas Maintenance Therapy in AML

NCT07493538Phase 2RecruitingPrimary

MT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan and Fludarabine, With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases

NCT06001788Phase 1RecruitingPrimary

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT06047886Phase 1RecruitingPrimary

UAB 2419-CD34 Selection Using the Automated CliniMACS Prodigy

NCT07516353Not ApplicableNot Yet Recruiting

my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young Adults

NCT05473910Phase 1RecruitingPrimary

A Study of TSC-100 and TSC-101 in AML, ALL and MDS in Patients Undergoing Allogeneic Peripheral Blood Stem Transplantation

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