Key Insights

Highlights

Success Rate

77% trial completion

Published Results

26 trials with published results (13%)

Research Maturity

72 completed trials (36% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

11.0%

22 terminated out of 200 trials

Success Rate

76.6%

-9.9% vs benchmark

Late-Stage Pipeline

7%

13 trials in Phase 3/4

Results Transparency

36%

26 of 72 completed with results

Key Signals

26 with results77% success22 terminated

Data Visualizations

Phase Distribution

172Total
Not Applicable (22)
Early P 1 (5)
P 1 (83)
P 2 (49)
P 3 (12)
P 4 (1)

Trial Status

Completed72
Recruiting43
Unknown29
Terminated22
Not Yet Recruiting11
Active Not Recruiting11

Trial Success Rate

76.6%

Benchmark: 86.5%

Based on 72 completed trials

Clinical Trials (200)

Showing 20 of 20 trials
NCT07702578Phase 3RecruitingPrimary

A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

NCT05473910Phase 1RecruitingPrimary

A Phase 1/3 Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

NCT03739502Phase 2Active Not RecruitingPrimary

A Randomized Phase II Study of Hyperbaric Oxygen in Improving Engraftment in Umbilical Cord Blood Stem Cell Transplant

NCT01096602Phase 2Completed

Blockade of PD-1 in Conjunction With the Dendritic Cell/AML Vaccine Following Chemotherapy Induced Remission

NCT07695571Not Yet Recruiting

Model-Informed Precision Dosing on Cyclosporine Therapy in Hematopoietic Stem Cell Transplant Recipients

NCT06664879Phase 1Active Not RecruitingPrimary

ALLG AMLM26 INTERCEPT (Investigating Novel Therapy to Target Early Relapse and Clonal Evolution as Pre-emptive Therapy in AML): A Multi-arm, Precision-based, Recursive, Platform Trial

NCT07661095Phase 1Recruiting

A Study of CRD3874-SI in People With Leukemia

NCT03050268Recruiting

Familial Investigations of Childhood Cancer Predisposition

NCT07490288Not ApplicableRecruitingPrimary

Venetoclax, Azacitidine and Liposomal Mitoxantrone for Newly Diagnosed AML

NCT06131801Recruiting

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

NCT07508982Phase 1RecruitingPrimary

Phase1b/2 Trial Of AZA + APG1252 In Patients With High-Risk AML

NCT07617285Phase 1RecruitingPrimary

Allogeneic CAR-T(CT0890B) in NKG2DL+ R/R AML

NCT05285813Phase 2TerminatedPrimary

A Phase II Study of Vibecotamab (XmAb14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure

NCT06973668Phase 2RecruitingPrimary

A Randomized Study to Compare Post-transplant Cyclophosphamide, Sirolimus, Ruxolitinib and Post-transplant Cyclophosphamide, Sirolimus, Mycophenolate Mofetil to Prevent Graft Versus Host Disease

NCT07587944RecruitingPrimary

Biomarkers in Bone Marrow Supernatant for Predicting AML Chemosensitivity

NCT06561880Phase 1Recruiting

The Efficacy of Triple Regimen in Newly Diagnosed AML Patients With FLT3 Mutation

NCT06611839Phase 1RecruitingPrimary

Venetoclax in Combination With Ivosidenib and Azacitidine for Newly Diagnosed IDH1-Mutated AML

NCT06744556Phase 2Active Not RecruitingPrimary

HAV Versus DAV/IAV Induction Regimen in Elderly Patients With AML

NCT04977180Phase 2RecruitingPrimary

Cardioprotection in AML

NCT06158828Phase 1Recruiting

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML

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