Key Insights

Highlights

Success Rate

77% trial completion

Published Results

26 trials with published results (13%)

Research Maturity

73 completed trials (36% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

10.9%

22 terminated out of 202 trials

Success Rate

76.8%

-9.7% vs benchmark

Late-Stage Pipeline

6%

13 trials in Phase 3/4

Results Transparency

36%

26 of 73 completed with results

Key Signals

26 with results77% success22 terminated

Data Visualizations

Phase Distribution

173Total
Not Applicable (22)
Early P 1 (5)
P 1 (83)
P 2 (50)
P 3 (12)
P 4 (1)

Trial Status

Completed73
Recruiting42
Unknown29
Terminated22
Active Not Recruiting12
Not Yet Recruiting12

Trial Success Rate

76.8%

Benchmark: 86.6%

Based on 73 completed trials

Clinical Trials (202)

Showing 20 of 20 trials
NCT05473910Phase 1RecruitingPrimary

A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation (ALLOHA)

NCT06131801Recruiting

Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

NCT07661095Phase 1Recruiting

A Study of CRD3874-SI in People With Leukemia

NCT07826897Not Yet RecruitingPrimary

Real-Time Breath Analysis in Acute Myeloid Leukaemia for a Rapid Characterisation of Biological Subtypes and to Predict Therapy Responses

NCT06946602Not ApplicableRecruitingPrimary

Conditioning Regimen in Elderly AML Patients Receiving Haplo-HSCT.

NCT00863148Phase 2Completed

Allogeneic Stem Cell Transplant With Clofarabine, Busulfan and Antithymocyte Globulin (ATG) for Adult Patients With High-risk Acute Myeloid Leukemia/Myelodysplastic Syndromes (AML/MDS) or Acute Lymphoblastic Leukemia (ALL)

NCT01188174Phase 2CompletedPrimary

Clofarabine/Ara-C Treatment Combined With Reduced-intensity Conditioning Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia in Primary Treatment Failure

NCT04061239Phase 2Completed

Comparison of Therapies Before Stem Cell Transplantation in Patients With Higher Risk MDS and Oligoblastic AML

NCT05153226Phase 3Active Not Recruiting

GvHD Prophylaxis in Unrelated Donor HCT: Randomized Trial Comparing PTCY Versus ATG

NCT06834282Phase 1RecruitingPrimary

CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), and Myelofibrosis (MF)

NCT06717958Phase 2RecruitingPrimary

Prospective Evaluation of Ivosidenib Maintenance Following Allogeneic Stem Cell Transplantation in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Neoplasia With IDH1 (Isocitrate Dehydrogenase 1) Mutation

NCT06158828Phase 1Recruiting

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML

NCT05796570Phase 2Active Not Recruiting

A Pilot Study to Evaluate the Feasibility of Post-Hematopoietic Stem Cell Transplant Prophylaxis With Decitabine Combined With Filgrastim for Children and Young Adults With AML, MDS and Related Myeloid Malignancies

NCT06001788Phase 1RecruitingPrimary

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT06529250Not ApplicableRecruitingPrimary

Intermediate-dose HAD Regimen for CEBPA Double-mutated AML

NCT06744504Phase 3RecruitingPrimary

Standard-dose vs Intermediate-dose Cytarabine Induction in the Treatment of Acute Myeloid Leukemia With RUNX1-RUNX1T1

NCT07490288Not ApplicableRecruitingPrimary

Venetoclax, Azacitidine and Liposomal Mitoxantrone for Newly Diagnosed AML

NCT06265545Not ApplicableRecruitingPrimary

Multicenter, Platform-type Clinical Study of Refractory/Recurrent Acute Myeloid Leukemia

NCT07748455Phase 2Not Yet RecruitingPrimary

HMA-Venetoclax Induction in Newly Diagnosed AML

NCT07702578Phase 3RecruitingPrimary

A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

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