NCT02606188

Brief Summary

The purpose of this study is to determine whether the Modified High-flow nasal cannula is effective in the oxygen of the patients undergoing bronchoscopy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
812

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2015

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2015

Completed
13 days until next milestone

First Submitted

Initial submission to the registry

November 14, 2015

Completed
3 days until next milestone

First Posted

Study publicly available on registry

November 17, 2015

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2019

Completed
Last Updated

August 19, 2020

Status Verified

August 1, 2020

Enrollment Period

4.1 years

First QC Date

November 14, 2015

Last Update Submit

August 18, 2020

Conditions

Bronchoscopy,Oxygen

Keywords

Modified High-flow nasal cannulaBronchoscopyOxygen therapy

Outcome Measures

Primary Outcomes (1)

  • the proportion of patients SpO2 < 90% during bronchoscopy

    1 hour

Secondary Outcomes (1)

  • the operation time

    1 hour

Study Arms (2)

Modified High-flow nasal cannula therapy

ACTIVE COMPARATOR

Patients undergoing bronchoscopy are given Modified High-flow nasal cannula oxygen therapy all the time.

Device: Modified High-flow nasal cannula

Nasal cnnnula therapy

ACTIVE COMPARATOR

Patients undergoing bronchoscopy are given nasal cannula oxygen therapy all the time.

Device: nasal cannula

Interventions

Modified High-flow nasal cannulaDEVICE

Modified High-flow nasal cannula

Modified High-flow nasal cannula therapy
nasal cannulaDEVICE

Conventional oxygen therap

Nasal cnnnula therapy

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age more than 18 years old;
  • need for bronchoscopy for diagnosis purpose.

You may not qualify if:

  • peripheral arterial pulse oximetry was \< 90%
  • platelet count \< 60 × 109/L;
  • nasopharyngeal obstruction or blockage.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of respiratory and critical care medicine,Beijing Chaoyang Hospital

Beijing, Beijing Municipality, 100020, China

Location

Related Publications (3)

  • Lucangelo U, Vassallo FG, Marras E, Ferluga M, Beziza E, Comuzzi L, Berlot G, Zin WA. High-flow nasal interface improves oxygenation in patients undergoing bronchoscopy. Crit Care Res Pract. 2012;2012:506382. doi: 10.1155/2012/506382. Epub 2012 May 20.

    PMID: 22666567RESULT

  • Diab S, Fraser JF. Maintaining Oxygenation Successfully with High Flow Nasal Cannula during Diagnostic Bronchoscopy on a Postoperative Lung Transplant Patient in the Intensive Care. Case Rep Crit Care. 2014;2014:198262. doi: 10.1155/2014/198262. Epub 2014 Nov 13.

    PMID: 25478241RESULT

  • Wang R, Li HC, Li XY, Tang X, Chu HW, Yuan X, Tong ZH, Sun B. Modified high-flow nasal cannula oxygen therapy versus conventional oxygen therapy in patients undergoing bronchoscopy: a randomized clinical trial. BMC Pulm Med. 2021 Nov 14;21(1):367. doi: 10.1186/s12890-021-01744-8.

    PMID: 34775948DERIVED

MeSH Terms

Interventions

Cannula

Intervention Hierarchy (Ancestors)

CathetersEquipment and Supplies

Study Officials

  • Bing Sun, MD

    Beijing Chao Yang Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Sponsor-Investigator

Study Record Dates

First Submitted

November 14, 2015

First Posted

November 17, 2015

Study Start

November 1, 2015

Primary Completion

December 1, 2019

Study Completion

December 1, 2019

Last Updated

August 19, 2020

Record last verified: 2020-08

Locations

CN(1)