Italian Registry On Multipoint Left Ventricular Pacing
IRON-MPP
1 other identifier
observational
436
1 country
3
Brief Summary
The IRON-MPP is a prospective multicenter, observational registry designed to collect clinical and device data from a large cohort of HF patients treated in clinical practice with a CRT-D device with the ability to deliver Multi Point Pacing. The purpose of the Registry is to collect data on how MPP-devices are being used by physicians in order to better understand how to improve the clinical care of patients and effectiveness of MPP therapy.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Aug 2013
Longer than P75 for all trials
3 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2013
CompletedFirst Submitted
Initial submission to the registry
November 6, 2015
CompletedFirst Posted
Study publicly available on registry
November 17, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2018
CompletedSeptember 26, 2017
September 1, 2017
3.1 years
November 6, 2015
September 25, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Left ventricular ejection fraction
Changes in Left ventricular ejection fraction
6 Months
Secondary Outcomes (4)
Heart Failure Hospitalizations
12 months
Appropriate device interventions
12 months
Echocardiographic changes
12 months
QRS Duration
Baseline and six months
Interventions
HF patients treated in clinical practice with a CRT-D device
Eligibility Criteria
HF patients treated in clinical practice with a CRT-D device with the ability to deliver MPP
You may qualify if:
- \- Patients implanted with a St. Jude Medical CRT-D system with MPP capability
You may not qualify if:
- \- Patients currently participating in any other clinical investigation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (3)
Ospedale Santa Maria della Misericordia
Rovigo, Italy
Casa Sollievo della Sofferenza
San Giovanni Rotondo, Italy
Ospedale Maria Vittoria
Torino, Italy
Related Publications (1)
Forleo GB, Santini L, Giammaria M, Potenza D, Curnis A, Calabrese V, Ricciardi D, D'agostino C, Notarstefano P, Ribatti V, Morani G, Mantica M, Di Biase L, Bertaglia E, Calo L, Zanon F. Multipoint pacing via a quadripolar left-ventricular lead: preliminary results from the Italian registry on multipoint left-ventricular pacing in cardiac resynchronization therapy (IRON-MPP). Europace. 2017 Jul 1;19(7):1170-1177. doi: 10.1093/europace/euw094.
PMID: 27189954DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Giovanni Forleo
Policlinico Tor Vergata
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 12 Months
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- MD
Study Record Dates
First Submitted
November 6, 2015
First Posted
November 17, 2015
Study Start
August 1, 2013
Primary Completion
September 1, 2016
Study Completion
September 1, 2018
Last Updated
September 26, 2017
Record last verified: 2017-09