NCT02605408

Brief Summary

The purpose of this study is to record and analyze the profile and outcome of cataract patients receiving phacoemulsification (phaco) and artificial intraocular lens (IOL) implantation with or without femtosecond laser-assisted cataract surgery (FLACS) in Indian tertiary medical centers.

Trial Health

15
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Apr 2016

Shorter than P25 for all trials

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 6, 2015

Completed
10 days until next milestone

First Posted

Study publicly available on registry

November 16, 2015

Completed
5 months until next milestone

Study Start

First participant enrolled

April 1, 2016

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2016

Completed
Last Updated

April 27, 2016

Status Verified

April 1, 2016

Enrollment Period

2 months

First QC Date

November 6, 2015

Last Update Submit

April 26, 2016

Conditions

Outcome Measures

Primary Outcomes (9)

  • Completion rate of an anterior capsulotomy

    Day 0, operative day

  • Best Corrected Visual Acuity (BCVA)

    Up to Day 30 postoperative

  • Uncorrected Visual Acuity (UCVA)

    Up to Day 30 postoperative

  • Cumulative dissipated energy (CDE)

    Cumulative Dissipated Energy (the amount of ultrasound energy entering the eye during the removal of the cataractous lens) will be reported on the Vision System interface and measured in percent-seconds.

    Day 0, operative day

  • Total phaco + IOL time

    Day 0, operative day

  • Aspiration fluid (ml)

    Day 0, operative day

  • Success rate of IOL insertion

    Day 0, operative day

  • Completion rate of cornea incision

    Day 0, operative day

  • Laser procedure time from suction on to off

    Day 0, operative day

Study Arms (1)

Cataract surgery

Phacoemulsification and artificial IOL implantation with and without LenSx® laser system

Device: LenSx® laser systemProcedure: Phacoemulsification

Interventions

Femtosecond laser system used for cornea incision, capsulotomy and lens fragmentation during cataract surgery

Cataract surgery

Removal of the cataractous lens

Cataract surgery

Eligibility Criteria

Age21 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Adults with cataracts who are receiving phacoemulsification (with or without LenSx® procedure) consecutively during the registry period

You may qualify if:

  • Agree to undergo phacoemulsification cataract surgery in at least 1 eye;
  • Understand and sign an informed consent form;

You may not qualify if:

  • Refuse to sign the informed consent form or have incomplete medical records;
  • Contraindications for phacoemulsification treatment per Investigator discretion or listed in LenSx® Operator's Manual;
  • Contraindications for anterior capsulotomy, phacofragmentation of the lens using the FLACS;

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Cataract

Interventions

Phacoemulsification

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Intervention Hierarchy (Ancestors)

Cataract ExtractionRefractive Surgical ProceduresOphthalmologic Surgical ProceduresSurgical Procedures, OperativeUltrasonic Surgical Procedures

Study Officials

  • Head Medical Affairs, MD

    Alcon India Pvt. Ltd.

    STUDY DIRECTOR
0

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 6, 2015

First Posted

November 16, 2015

Study Start

April 1, 2016

Primary Completion

June 1, 2016

Study Completion

June 1, 2016

Last Updated

April 27, 2016

Record last verified: 2016-04