Cognitive Ability Training in Seniors
CATS
Verbesserung Kognitiver Fähigkeiten im Alter
1 other identifier
interventional
38
1 country
1
Brief Summary
This study investigates the beneficial effects of prefrontal brain stimulation (with transcranial direct current stimulation \[tDCS\]) during working memory training in seniors with subjective memory impairments.The placebo-controlled double blinded study includes 50 elderly probands which were randomized into verum or sham tDCS.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started May 2015
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2015
CompletedFirst Submitted
Initial submission to the registry
June 16, 2015
CompletedFirst Posted
Study publicly available on registry
October 27, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2016
CompletedResults Posted
Study results publicly available
March 12, 2024
CompletedMarch 12, 2024
March 1, 2024
1.4 years
June 16, 2015
August 31, 2022
March 11, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Neuropsychological Performance in Neuropsychological Test: Verbal Learning Memory Test (VLMT)
The Investigators are measuring cognitive performance for different executive functions, here the score (percentile of the norm values) of the test verbal learning memory test (VLMT), parameter immediate recall post treatment is reported. Rage from 0 to 100 %. Higher values indicate higher performance.
4 weeks
Secondary Outcomes (1)
Brain Activation Measured With Near-infrared Spectroscopy (NIRS) During the Semantic Condition of the Verbal Fluency Task (VFT)
4 weeks
Study Arms (2)
Verum tDCS
EXPERIMENTALLeft frontal anodal stimulation, supraorbital right cathodal stimulation
Sham tDCS
EXPERIMENTALsham stimulation, same electrode positions
Interventions
Neuropsychological (Working memory) training for 30 minutes, 6 sessions tDCS during training with 2000 microampere left anodal, right cathodal
Neuropsychological (Working memory) training for 30 minutes, 6 sessions tDCS during training with 0 microampere
Eligibility Criteria
You may qualify if:
- native german speaker
- between 60-70 years old
- subjective memory impairment
You may not qualify if:
- psychiatric, neurological diseases
- uncorrected hearing or vision deficits
- actual psychopharmaco intake
- metal parts in the head
- medical electronical implants
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University hospital
Würzburg, 97080, Germany
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Results Point of Contact
- Title
- Prof. Dr. Martin Herrmann
- Organization
- Universitätsklinikum Würzburg
Study Officials
- PRINCIPAL INVESTIGATOR
Martin J. Herrmann, PD Dr
University of Würzburg
Publication Agreements
- PI is Sponsor Employee
- Yes
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 16, 2015
First Posted
October 27, 2015
Study Start
May 1, 2015
Primary Completion
October 1, 2016
Study Completion
December 1, 2016
Last Updated
March 12, 2024
Results First Posted
March 12, 2024
Record last verified: 2024-03