Long-term Outcome of End-stage Renal Disease Patients Treated With Hig-efficiency Hemodiafiltration

NCT02576873 | Completed

• 1 other identifier: 455/56
• Study Type: observational
• Target: 66
• Locations: 1 country
• Sites: 1

Brief Summary

A retrospective cohort study was conducted in 66 end-stage renal disease patients who underwent high-efficiency hemodiafiltration technique in King Chulalongkorn Memorial Hospital between 2001-2013 to determine the survival rate as well as other long-term outcome.

Conditions

End-stage Renal Disease

Keywords

Survival; Hemodiafiltration; End-stage renal disease; Hemodialysis

Outcome Measures

Primary Outcomes (1)

• Survival rate

  The Kaplan-Meier survival curve and mean survival time will be demonstrated for primary outcome.

  10 years

Secondary Outcomes (2)

• Comparison of survival differences between patients who start renal replacement therapy with HDF and who switched from hemodialysis as well as between diabetic and non-diabetic patient.

  10 years

• Factors that associated with all-cause mortality

  10 years

Study Arms (1)

Hemodiafiltration

End-stage renal disease patients who were treated with high-efficiency hemodiafiltration for more than 6 months

Other: Hemodiafiltration

Interventions

Hemodiafiltration OTHER

Hemodiafiltration treatments were prescribed to the patients as their long-term renal replacement therapies

Hemodiafiltration

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

End-stage renal disease patients who had been received long-term hemodiafiltration at King Chulalongkorn Memorial hospital during 2001-2013

You may qualify if:

• Aged 18 years or more
• Be diagnosed end-stage renal disease for more than one year
• Have been regularly received long-term hemodiafiltration for more than 6 months.

You may not qualify if:

• Patients who received hemodiafiltration less than 6 months

Sponsors & Collaborators

• Chulalongkorn University: lead

Study Sites (1)

King Chulalongkorn Memorial Hospital

Pathumwan, Bangkok, 10330, Thailand

Location

MeSH Terms

Conditions

Kidney Failure, Chronic

Interventions

Hemodiafiltration

Condition Hierarchy (Ancestors)

Renal Insufficiency, Chronic; Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Renal Dialysis; Renal Replacement Therapy; Therapeutics; Sorption Detoxification; Hemofiltration; Extracorporeal Circulation; Surgical Procedures, Operative

Study Officials

• Khajohn Tiranathanagul, MD

  Chulalongkorn University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: October 13, 2015
• First Posted: October 15, 2015
• Study Start: March 1, 2014
• Primary Completion: October 1, 2015
• Study Completion: March 1, 2016
• Last Updated: July 28, 2016

Record last verified: 2016-07

Data Sharing

• IPD Sharing: Will not share

Locations

TH (1)