NCT02573103

Brief Summary

To determine the effects of ambient airpollution exposures on cardiovascular responses among healthy adults without cardiovascular disease.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
73

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Nov 2014

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2014

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

September 28, 2015

Completed
11 days until next milestone

First Posted

Study publicly available on registry

October 9, 2015

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2016

Completed
Last Updated

July 12, 2018

Status Verified

July 1, 2018

Enrollment Period

1.2 years

First QC Date

September 28, 2015

Last Update Submit

July 10, 2018

Conditions

Metabolic Disorder

Outcome Measures

Primary Outcomes (1)

  • Dyslipidemia

    Analyzed HDL by Beckman AU5800

    One year

Secondary Outcomes (1)

  • System oxidative stress

    One year

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

We will maintain enrollment criteria of the in-progress study being healthy adults without CV disease or risk factors

You may qualify if:

  • without CV disease or risk factors (e.g., hypertension, diabetes, or treated hyperlipidemia). Subjects are non-smokers in non-smoking household.

You may not qualify if:

  • Screening visit BP\>140/90 mm Hg, fasting glucose \>126 mg/dL, or positive urine pregnancy test (females). Subjects cannot be taking any medications or over-the-counter drugs that affect CV function.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Biospecimen

Retention: SAMPLES WITHOUT DNA

plasma and urine

MeSH Terms

Conditions

Metabolic Diseases

Condition Hierarchy (Ancestors)

Nutritional and Metabolic Diseases

Study Officials

  • Wei Huang, PhD

    Peking University School of Public Health

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Peking University School of Public Health

Study Record Dates

First Submitted

September 28, 2015

First Posted

October 9, 2015

Study Start

November 1, 2014

Primary Completion

January 1, 2016

Study Completion

January 1, 2016

Last Updated

July 12, 2018

Record last verified: 2018-07