NCT02561754

Brief Summary

The goal of this study is to explore the impact of two different diets (conventional vs. enhanced stop light) and two different delivery systems (face-to-face vs. remote) on weight across 18 months in overweight and obese adolescents with intellectual and developmental disabilities.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
110

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2015

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2015

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

June 25, 2015

Completed
3 months until next milestone

First Posted

Study publicly available on registry

September 28, 2015

Completed
4.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 12, 2020

Completed
12 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 5, 2021

Completed
1.8 years until next milestone

Results Posted

Study results publicly available

February 10, 2023

Completed
Last Updated

February 10, 2023

Status Verified

February 1, 2023

Enrollment Period

5.2 years

First QC Date

June 25, 2015

Results QC Date

December 12, 2022

Last Update Submit

February 7, 2023

Conditions

Keywords

DietObesityAdolescentsIntellectual and Developmental Disability

Outcome Measures

Primary Outcomes (1)

  • Weight Change at 6 Months

    Participants will be weighed in shorts and a t-shirt , on a calibrated scale to the nearest 0.1 kg.

    Change in weight from baseline to 6 months

Secondary Outcomes (1)

  • Weight Change Across 18 Months

    Change in weight from baseline to 18 months

Study Arms (3)

Face-To-Face/CD

ACTIVE COMPARATOR

Delivery: Face-to-face Diet: Conventional diet

Dietary Supplement: Conventional Diet (CD)Behavioral: Face-to-face (FTF)

Technology delivery/CD

EXPERIMENTAL

Delivery: Technology Diet: Conventional diet

Dietary Supplement: Conventional Diet (CD)Behavioral: Technology (TECH)Other: iPad with FaceTime

Technology delivery/eSLD

EXPERIMENTAL

Delivery: Technology Diet: enhanced Stop Light Diet

Dietary Supplement: Enhanced Stop Light Diet (eSLD)Behavioral: Technology (TECH)Other: iPad with FaceTime

Interventions

eSDL includes reduced energy portion controlled meals for 6 months, encouraged consumption of lower energy shakes and 35 fruits and vegetables per week.

Technology delivery/eSLD
Conventional Diet (CD)DIETARY_SUPPLEMENT

CD is a nutritionally balanced, reduced energy, high volume, lower fat ( fat=20-30% energy) diet.

Face-To-Face/CDTechnology delivery/CD

FTF will meet with a health educator in person and will track progress using pen and paper records for both physical activity and diet.

Face-To-Face/CD

TECH groups will receive the intervention using an iPad with the FaceTimeTM application for video meetings with a health educator and will track progress using the Lose it! application for both physical activity and diet.

Technology delivery/CDTechnology delivery/eSLD

TECH groups will receive the intervention using an iPad with the FaceTimeTM to the intervention field.

Technology delivery/CDTechnology delivery/eSLD

Eligibility Criteria

Age13 Years - 21 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Age 13-21 yrs
  • Mild (IQ of 74-50) or moderate (IQ 40-49) IDD,
  • Of sufficient functional ability to understand directions, communicate preferences (e.g. foods), wants (e.g. more to eat/drink), and needs (e.g. assistance with food preparation) through spoken language.
  • Overweight or obese (BMI ≥ 85th%ile on CDC growth charts, or waist circumference to height ratio \> 0.5
  • Living at home with a parent or guardian.
  • Internet access in the home.
  • No plans to relocate outside the study area over the next 18 mos
  • Physician consent for PA and diet.

You may not qualify if:

  • Insulin dependent diabetes
  • Participation in a weight management program involving diet and PA in the past 6 mos
  • Eating disorders, serious food allergies, consuming special diets, aversion to common foods,
  • Diagnosis of Prader-Willi Syndrome
  • Currently pregnant, planning on/becoming pregnant during the study.
  • Unable to participate in moderate to vigorous PA.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

University of Kansas Medical Center

Kansas City, Kansas, 66160, United States

Location

Energy Balance Lab, The University of Kansas

Lawrence, Kansas, 66045, United States

Location

Related Publications (4)

  • Bodde AE, White DA, Forseth B, Hastert M, Washburn R, Donnelly J, Sullivan D, Ptomey LT. Parent factors associated with BMI, diet, and physical activity of adolescents with intellectual and developmental disabilities. Disabil Health J. 2023 Oct;16(4):101507. doi: 10.1016/j.dhjo.2023.101507. Epub 2023 Jul 7.

  • Bodde AE, Helsel BC, Hastert M, Suire KB, Washburn RA, Donnelly JE, Ptomey LT. The prevalence of obesity and lifestyle behaviors of parents of youth with intellectual and developmental disabilities. Disabil Health J. 2023 Jul;16(3):101430. doi: 10.1016/j.dhjo.2022.101430. Epub 2022 Dec 14.

  • Ptomey LT, Lee J, White DA, Helsel BC, Washburn RA, Donnelly JE. Changes in physical activity across a 6-month weight loss intervention in adolescents with intellectual and developmental disabilities. J Intellect Disabil Res. 2022 Jun;66(6):545-557. doi: 10.1111/jir.12909. Epub 2021 Dec 16.

  • Ptomey LT, Washburn RA, Goetz JR, Sullivan DK, Gibson CA, Mayo MS, Krebill R, Gorczyca AM, Montgomery RN, Honas JJ, Helsel BC, Donnelly JE. Weight Loss Interventions for Adolescents With Intellectual Disabilities: An RCT. Pediatrics. 2021 Sep;148(3):e2021050261. doi: 10.1542/peds.2021-050261. Epub 2021 Aug 19.

MeSH Terms

Conditions

Developmental DisabilitiesWeight LossBody WeightDown SyndromeBody Weight ChangesIntellectual DisabilityObesity

Interventions

Technology

Condition Hierarchy (Ancestors)

Neurodevelopmental DisordersMental DisordersSigns and SymptomsPathological Conditions, Signs and SymptomsNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesAbnormalities, MultipleCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesChromosome DisordersGenetic Diseases, InbornOverweightOvernutritionNutrition DisordersNutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Technology, Industry, and Agriculture

Results Point of Contact

Title
Dr. Joseph Donnelly
Organization
University of Kansas Medical Center

Study Officials

  • Joseph E Donnelly, EdD

    University of Kansas Medical Center

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 25, 2015

First Posted

September 28, 2015

Study Start

March 1, 2015

Primary Completion

May 12, 2020

Study Completion

May 5, 2021

Last Updated

February 10, 2023

Results First Posted

February 10, 2023

Record last verified: 2023-02

Locations