Apraxia of Speech: Comparison of EPG Treatment (Tx) and Sound Production Treatment (SPT)

NCT02554513 | Completed Results

• 1 other identifier: C2068-P
• Study Type: interventional
• Target: 6
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the proposed research is to examine the effects of two treatment approaches on speech production involving speakers with chronic apraxia of speech (AOS) and aphasia. The planned investigation is designed to examine the acquisition, maintenance and generalization effects of each treatment. One approach, electropalatography (EPG) uses visual biofeedback in conjunction with articulatory-kinematic treatment and the other approach, sound production treatment (SPT) is one of the most systematically studied articulatory-kinematic treatments for AOS.

Conditions

Apraxia of Speech; Aphasia, Acquired; Speech Disorders

Keywords

Apraxia of Speech; Treatment

Outcome Measures

Primary Outcomes (1)

• Speech Production: Percent Change in Treated Items Immediately Post Treatment

  Change in accuracy of articulation of treated items measured by percent increase in accuracy above the highest baseline measurement; production of words designated for treatment was measured repeatedly in non-treatment probes prior to treatment, throughout all study phases and immediately post treatment with percent accuracy calculated for each probe (0% to 100% correct). The highest percentage accuracy achieved in baseline probes was subtracted from the percentage accuracy achieved at the conclusion of treatment to obtain change in accuracy value - this reflects change from maximum correct performance in baseline (baseline). e.g., if in baseline probes, performance ranged from 10% to 30% accuracy and at post treatment performance was 90% accuracy, the change value would be 60% (90% minus 30%). A greater value indicates greater change in articulation/production of words. Change could be positive (improved articulation) or negative (poorer articulation)

  Baseline vs. Immediately Post Treatment (7 week treatment period)

Secondary Outcomes (4)

• Speech Production: Percent Change in Untreated Items (Related Items) Immediately Post Treatment

  Baseline vs. Immediately Post Treatment (7 week treatment period)

• Speech Production: Percent Change for Treated Items After the Completion of Treatment

  Baseline vs. 7 weeks post treatment [measured immediately after the completion of each treatment]

• Functional Communication Skills: T-Score

  Baseline vs. 10 weeks after the completion of all treatment [measured at pre-treatment and post-treatment; conclusion of all treatment]

• Speech Intelligibility: Percentage

  Baseline vs. 10 weeks post all treatment [measured at pre-treatment and post-treatment; conclusion of all treatment]

Study Arms (2)

EPG Tx

ACTIVE COMPARATOR

An articulatory-kinematic treatment in conjunction with visual biofeedback specifically tongue to palate contact to improve speech production

Device: EPG Tx

Sound Production Treatment (SPT)

ACTIVE COMPARATOR

An articulatory-kinematic treatment that uses integral stimulation to improve speech production.

Behavioral: SPT

Interventions

EPG Tx DEVICE

behavioral intervention that incorporates a device that provides visual biofeedback

Also known as: Electropalatography Treatment, Palatometer Treatment

EPG Tx

SPT BEHAVIORAL

A treatment hierarchy involving integral stimulation

Also known as: Sound Production Treatment

Sound Production Treatment (SPT)

Eligibility Criteria

• Age: 21 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Veterans or non Veterans with apraxia of speech who reside in the Salt Lake City region (commutable),
• months or more post stroke or other focal brain injury, no other neurological conditions
• native English speakers, hearing adequate for experimental task (e.g., pass puretone screening at 35dB at 500, 1K, 2K Hz or adequate aided hearing)
• non linguistic cognition within normal limits

You may not qualify if:

• less than 6 months post stroke
• insufficient hearing, insufficient non linguistic cognitive skills
• neurological conditions other than stroke
• unable to attend treatment in the Salt Lake City vicinity

Sponsors & Collaborators

• VA Office of Research and Development: lead

Study Sites (1)

VA Salt Lake City Health Care System, Salt Lake City, UT

Salt Lake City, Utah, 84148, United States

Location

Related Publications (1)

• Mauszycki SC, Wambaugh JL. Acquired Apraxia of Speech: Comparison of Electropalatography Treatment and Sound Production Treatment. Am J Speech Lang Pathol. 2020 Feb 21;29(1S):511-529. doi: 10.1044/2019_AJSLP-CAC48-18-0223. Epub 2019 Nov 6.

  PMID: 31693389 DERIVED

MeSH Terms

Conditions

Apraxias; Aphasia; Speech Disorders

Condition Hierarchy (Ancestors)

Psychomotor Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Language Disorders; Communication Disorders

Results Point of Contact

• Title: Dr. Shannon Mauszycki
• Organization: VASLCHCS

shannon.mauszycki@utah.edu

801-582-1565

Study Officials

• Shannon C Mauszycki, PhD

  VA Salt Lake City Health Care System, Salt Lake City, UT

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: Single
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: FED
• Responsible Party: SPONSOR

Model Details: Each participant received each arm of treatment

Study Record Dates

• First Submitted: August 19, 2015
• First Posted: September 18, 2015
• Study Start: November 2, 2015
• Primary Completion: February 1, 2019
• Study Completion: June 28, 2019
• Last Updated: November 4, 2021
• Results First Posted: November 4, 2021

Record last verified: 2021-10

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)