Effect of the Position of the Patient's Head

NCT02549313 | Completed

• 2 other identifiers: 11081832011-A01565-36
• Study Type: observational
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

The position of the head of the patient influences the cerebral venous return and cerebral perfusion pressure (CPP). In our daily practice, it is almost routine to prescribe a Trendelenburg position 30 ° in all brain-damaged patients. However, this is based only on precarious bibliographic databases. It has been shown to decrease the Intracranial Pressure (ICP) in Trendelenburg position relative to the horizontal, with varying effects on PPC. Effects on sylvian objectified by Doppler velocities and cerebral oxygenation seem unaffected by changes of position of the head of the patient. But the whole of the literature on this subject has significant bias.

Conditions

Brain Lesion

Keywords

brain lesion; intracranial pressure; cerebral perfusion pressure

Outcome Measures

Primary Outcomes (1)

• Cerebral oxygenation

  Value of cerebral oxygenation (Hg mm) after 5 minutes in each position

  day 1

Study Arms (1)

position changes of head with brain lesion

patient with position changes of the head: registration of blood flow changes induced when the patient's head will be tilted at 0 ° (that is to say flat), 15 ° and 30 °.

Procedure: position changes of the head

Interventions

position changes of the head PROCEDURE

Registration of blood flow changes induced when the patient's head will be tilted at 0 ° (that is to say flat), 15 ° and 30 ° (the order of actions will be determined by drawing lots). The patient will remain 10 minutes in each of these positions.

position changes of head with brain lesion

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patient with brain lesion

You may qualify if:

• Patients aged over 18 years with:
• A severe head injury
• or subarachnoid hemorrhage before the 5th day of evolution
• or spontaneous intracranial hematoma
• or ischemic stroke
• Neurosurgical Patients after surgery
• Presenting intracranial hypertension

You may not qualify if:

• Hemodynamic and / or neurological instability. In the most unstable patients, care and mobilizations are reduced to a minimum.
• Craniectomy

Sponsors & Collaborators

• Centre Hospitalier Universitaire de Saint Etienne: lead

Study Sites (1)

CHU de SAINT-ETIENNE

Saint-Etienne, 42000, France

Location

Biospecimen

Retention: SAMPLES WITH DNA

blood sample

Study Officials

• Laurent GERGELE, MD

  CHU de SAINT-ETIENNE

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 11, 2015
• First Posted: September 15, 2015
• Study Start: January 1, 2012
• Primary Completion: October 1, 2015
• Study Completion: October 1, 2015
• Last Updated: November 3, 2015

Record last verified: 2015-11

Locations

FR (1)