The Effect of Altered Gravity Condition on Postural Control

NCT02517229 | Unknown

• 1 other identifier: 12-084
• Study Type: interventional
• Target: 18
• Locations: 1 country
• Sites: 1

Brief Summary

The scientific goal of this experiment is to evaluate changes in balance control in response to microgravity during reactive balance tasks. For that purpose, kinematic and neuromuscular parameters under microgravity are compared to normal gravity conditions. To induce postural responses among the test subjects, an electromagnetic maneuverable postural platform will be used in order to randomly elicit perturbations. Postural reactions will be quantified by means of mechanical and electromyographic data. In Addition, peripheral nerve stimulation will be used to assess the spinal excitability by means of H-reflex recordings. H-reflex measurements were chosen as they allow reliable information about inhibitory and facilitatory mechanisms taking place at the spinal level.

Conditions

Healthy

Keywords

volunteers

Outcome Measures

Primary Outcomes (3)

• balance skill, expressed by the postural sway in mm

  baseline

• neuromuscular activity, expressed by the Electromyograpy (EMG)-amplitudes

  baseline

• spinal excitability, expressed by H-Reflexes

  baseline

Study Arms (1)

in balance control in response to microgravity

OTHER

to evaluate changes in balance control in response to microgravity during reactive balance tasks compared to normal gravity.

Other: Parabolic flight; Other: balance control measurements; Device: electromagnetic maneuverable postural platform

Interventions

Parabolic flight OTHER

in balance control in response to microgravity

balance control measurements OTHER

in balance control in response to microgravity

electromagnetic maneuverable postural platform DEVICE

in balance control in response to microgravity

Eligibility Criteria

• Age: 21 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthy volunteers (men or women)
• Aged from 21 to 65
• Affiliated to a Social Security system and, for non-French resident, holding a European Health Insurance Card (EHIC)
• Who accepted to take part in the study
• Who have given their written stated consent
• Who has passed a medical examination similar to a standard aviation medical examination for private pilot aptitude. There will be no additional test performed for subject selection.

You may not qualify if:

• Person with medical history of neurological disorders
• Person with medical history of musculoskeletal disorders of the lower limbs, especially of the ankle and knee joint.
• Pregnant women

Sponsors & Collaborators

• University Hospital, Caen: lead

Study Sites (1)

Umr Ucbn/Inserm U1075 Comete

Caen, Basse-Normandie, 14032, France

RECRUITING

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 23, 2015
• First Posted: August 6, 2015
• Study Start: September 1, 2012
• Primary Completion: October 1, 2015
• Last Updated: August 6, 2015

Record last verified: 2015-08

Locations

FR (1)