NCT02516878

Brief Summary

In this study, a 18-week, single-blinded, randomized controlled clinical trial will be conducted to evaluate the effectiveness, efficacy and safety of acupuncture on weight control in Hong Kong.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
72

participants targeted

Target at P50-P75 for not_applicable obesity

Timeline
Completed

Started Aug 2015

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 30, 2015

Completed
2 days until next milestone

Study Start

First participant enrolled

August 1, 2015

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 6, 2015

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2016

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2016

Completed
Last Updated

March 15, 2017

Status Verified

March 1, 2017

Enrollment Period

1.2 years

First QC Date

July 30, 2015

Last Update Submit

March 14, 2017

Conditions

Keywords

acupunctureChinese Medicineobesity

Outcome Measures

Primary Outcomes (1)

  • Change in body weight during treatment and follow up

    measured by Omron KARADA Scan Body Composition \& Scale

    The change in body weight will be assessed every two weeks during 8-week treatment and 8-week follow up

Secondary Outcomes (5)

  • Change in Body Mass Index (BMI) during treatment and follow up

    The change in BMI will be assessed every two weeks during 8-week treatment and 8-week follow up

  • Change in waist circumference during treatment and follow up

    The change in waist circumference will be assessed every two weeks during 8-week treatment and 8-week follow up

  • Change in hip circumference

    The change in hip circumference will be assessed every two weeks during 8-week treatment and 8-week follow up

  • Change in body fat percentage during treatment and follow up

    The change in body fat percentage will be assessed every two weeks during 8-week treatment and 8-week follow up

  • Number of patients with adverse events after treatment

    Number of patients with adverse events after treatment will be recorded and compared among the two groups during 8-week treatment and 8-week follow up

Study Arms (2)

Acupuncture group

EXPERIMENTAL

Eight body acupuncture points will be chosen as Tianshu(ST-25), Daheng(SP-15), Daimai(GB-26), Qihai(CV-6), Zhongwan(CV-12), Zusanli(ST-36), Fenlong(ST-40), Sanyinjiao(SP-6). The needles will be retained for 30 minutes. Participants of the treatment group will additionally receive unilateral auricular acupressure at four auricular points as Hunger, Shen men, Spleen and Stomach with Semen Vaccariae embedded within adhesive tape in each treatment session. Acupressure will be applied by the subjects with repeat pressing of the tape with fingertips for 3 minutes per point, 3 times per day. The embedded tape will be retained in-situ until the next visit and then the alternate side of ear will be treated.

Procedure: Acupuncture

Control group

SHAM COMPARATOR

For subjects assigned to control group, Streitberger's non-invasive acupuncture needles (Gauge 8 x 1.2" / 0.30 x 30 mm) will be applied to serve as sham control at the same acupoints with the same stimulation modality, except that the needles are only adhered to the skin instead of insertion. The Semen Vaccariae embedded tape used in treatment group will be applied on 4 non-acupoints at the helix unilaterally, retained until the next visit and then the alternate ear will be used.

Procedure: Acupuncture

Interventions

AcupuncturePROCEDURE

Eight body acupuncture points will be chosen as Tianshu(ST-25), Daheng(SP-15), Daimai(GB-26), Qihai(CV-6), Zhongwan(CV-12), Zusanli(ST-36), Fenlong(ST-40), Sanyinjiao(SP-6). The needles will be retained for 30 minutes. Participants of the treatment group will additionally receive unilateral auricular acupressure at four auricular points as Hunger, Shen men, Spleen and Stomach with Semen Vaccariae embedded within adhesive tape in each treatment session. Acupressure will be applied by the subjects with repeat pressing of the tape with fingertips for 3 minutes per point, 3 times per day. The embedded tape will be retained in-situ until the next visit and then the alternate side of ear will be treated.

Acupuncture groupControl group

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • aged between 18 and 65 years old;
  • body mass index (BMI)≥25 kg/m2;
  • having not received any other weight control measures or any medical and/or drug history within the last 3 months.

You may not qualify if:

  • endocrine diseases;
  • heart diseases;
  • patients with pacemaker;
  • allergy and immunology diseases;
  • having bleeding tendency;
  • pregnant or lactating women;
  • having impaired hepatic or renal function;
  • stroke or otherwise unable to exercise.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Zhong LL, Kun W, Lam TF, Zhang SP, Yang JJ, Ziea TC, Ng B, Bian ZX. The combination effects of body acupuncture and auricular acupressure compared to sham acupuncture for body weight control: study protocol for a randomized controlled trial. Trials. 2016 Jul 25;17(1):346. doi: 10.1186/s13063-016-1458-2.

MeSH Terms

Conditions

Obesity

Interventions

Acupuncture Therapy

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Complementary TherapiesTherapeutics

Study Officials

  • Zhaoxiang Bian, MD., Ph.D

    Hong Kong Baptist University

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

July 30, 2015

First Posted

August 6, 2015

Study Start

August 1, 2015

Primary Completion

October 1, 2016

Study Completion

December 1, 2016

Last Updated

March 15, 2017

Record last verified: 2017-03