NCT02511470

Brief Summary

The purpose of this study is to determine if the use of a metronome improves chest compression rate and depth during cardiopulmonary resuscitation (CPR) on a pediatric manikin.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
155

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Oct 2013

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2013

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2014

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

July 22, 2015

Completed
8 days until next milestone

First Posted

Study publicly available on registry

July 30, 2015

Completed
Last Updated

July 30, 2015

Status Verified

July 1, 2015

Enrollment Period

9 months

First QC Date

July 22, 2015

Last Update Submit

July 27, 2015

Conditions

Cardiac Arrest

Keywords

Cardiopulmonary ResuscitationPediatric simulation studyMetronome

Outcome Measures

Primary Outcomes (1)

  • Metronome effect on compression rate and depth

    The mean of the percentage of compressions that were within an adequate rate (90-110 per minute) and adequate depth (38-51mm) with and without the metronome.

    Adequacy of chest compressions (in terms of rate and depth) under each intervention (with and without metronome) was assessed during two minutes

Study Arms (2)

CPR with metronome on

OTHER

Participants will perform two minutes of uninterrupted chest compressions on a pediatric manikin with the metronome on. Data for compression rate and depth will be collected during this time interval.

Other: Metronome on

CPR with metronome off

OTHER

Participants will perform two minutes of uninterrupted chest compressions on a pediatric manikin with the metronome off. Data for compression rate and depth will be collected during this time interval.

Other: Metronome off

Interventions

Metronome onOTHER

Metronome on during participants performance of CPR on a pediatric manikin

CPR with metronome on
Metronome offOTHER

Metronome off during participants performance of CPR on a pediatric manikin

CPR with metronome off

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • health professionals with a minimum of basic life support training according to the 2010 AHA guidelines capable of performing chest compressions.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (18)

  • Abella BS, Sandbo N, Vassilatos P, Alvarado JP, O'Hearn N, Wigder HN, Hoffman P, Tynus K, Vanden Hoek TL, Becker LB. Chest compression rates during cardiopulmonary resuscitation are suboptimal: a prospective study during in-hospital cardiac arrest. Circulation. 2005 Feb 1;111(4):428-34. doi: 10.1161/01.CIR.0000153811.84257.59.

    PMID: 15687130BACKGROUND

  • Al-Shamsi M, Al-Qurashi W, de Caen A, Bhanji F. Pediatric basic and advanced life support: an update on practice and education. Oman Med J. 2012 Nov;27(6):450-4. doi: 10.5001/omj.2012.108.

    PMID: 23226814BACKGROUND

  • Bohn A, Weber TP, Wecker S, Harding U, Osada N, Van Aken H, Lukas RP. The addition of voice prompts to audiovisual feedback and debriefing does not modify CPR quality or outcomes in out of hospital cardiac arrest--a prospective, randomized trial. Resuscitation. 2011 Mar;82(3):257-62. doi: 10.1016/j.resuscitation.2010.11.006. Epub 2010 Dec 13.

    PMID: 21146279BACKGROUND

  • Dine CJ, Gersh RE, Leary M, Riegel BJ, Bellini LM, Abella BS. Improving cardiopulmonary resuscitation quality and resuscitation training by combining audiovisual feedback and debriefing. Crit Care Med. 2008 Oct;36(10):2817-22. doi: 10.1097/CCM.0b013e318186fe37.

    PMID: 18766092BACKGROUND

  • Fitzgerald KR, Babbs CF, Frissora HA, Davis RW, Silver DI. Cardiac output during cardiopulmonary resuscitation at various compression rates and durations. Am J Physiol. 1981 Sep;241(3):H442-8. doi: 10.1152/ajpheart.1981.241.3.H442.

    PMID: 7282953BACKGROUND

  • Handley AJ, Handley SA. Improving CPR performance using an audible feedback system suitable for incorporation into an automated external defibrillator. Resuscitation. 2003 Apr;57(1):57-62. doi: 10.1016/s0300-9572(02)00400-8.

    PMID: 12668300BACKGROUND

  • Hurst VW 4th, Whittam SW, Austin PN, Branson RD, Beck G. Cardiopulmonary resuscitation during spaceflight: examining the role of timing devices. Aviat Space Environ Med. 2011 Aug;82(8):810-3. doi: 10.3357/asem.2284.2011.

    PMID: 21853860BACKGROUND

  • Jantti H, Silfvast T, Turpeinen A, Kiviniemi V, Uusaro A. Influence of chest compression rate guidance on the quality of cardiopulmonary resuscitation performed on manikins. Resuscitation. 2009 Apr;80(4):453-7. doi: 10.1016/j.resuscitation.2009.01.001. Epub 2009 Feb 8.

    PMID: 19203821BACKGROUND

  • Kern KB, Hilwig RW, Berg RA, Ewy GA. Efficacy of chest compression-only BLS CPR in the presence of an occluded airway. Resuscitation. 1998 Dec;39(3):179-88. doi: 10.1016/s0300-9572(98)00141-5.

    PMID: 10078808BACKGROUND

  • Kern KB. Cardiopulmonary resuscitation without ventilation. Crit Care Med. 2000 Nov;28(11 Suppl):N186-9. doi: 10.1097/00003246-200011001-00003.

    PMID: 11098942BACKGROUND

  • Kern KB, Stickney RE, Gallison L, Smith RE. Metronome improves compression and ventilation rates during CPR on a manikin in a randomized trial. Resuscitation. 2010 Feb;81(2):206-10. doi: 10.1016/j.resuscitation.2009.10.015. Epub 2009 Nov 18.

    PMID: 19926194BACKGROUND

  • Kleinman ME, Chameides L, Schexnayder SM, Samson RA, Hazinski MF, Atkins DL, Berg MD, de Caen AR, Fink EL, Freid EB, Hickey RW, Marino BS, Nadkarni VM, Proctor LT, Qureshi FA, Sartorelli K, Topjian A, van der Jagt EW, Zaritsky AL. Part 14: pediatric advanced life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2010 Nov 2;122(18 Suppl 3):S876-908. doi: 10.1161/CIRCULATIONAHA.110.971101. No abstract available.

    PMID: 20956230BACKGROUND

  • Kramer-Johansen J, Myklebust H, Wik L, Fellows B, Svensson L, Sorebo H, Steen PA. Quality of out-of-hospital cardiopulmonary resuscitation with real time automated feedback: a prospective interventional study. Resuscitation. 2006 Dec;71(3):283-92. doi: 10.1016/j.resuscitation.2006.05.011. Epub 2006 Oct 27.

    PMID: 17070980BACKGROUND

  • Matos RI, Watson RS, Nadkarni VM, Huang HH, Berg RA, Meaney PA, Carroll CL, Berens RJ, Praestgaard A, Weissfeld L, Spinella PC; American Heart Association's Get With The Guidelines-Resuscitation (Formerly the National Registry of Cardiopulmonary Resuscitation) Investigators. Duration of cardiopulmonary resuscitation and illness category impact survival and neurologic outcomes for in-hospital pediatric cardiac arrests. Circulation. 2013 Jan 29;127(4):442-51. doi: 10.1161/CIRCULATIONAHA.112.125625. Epub 2013 Jan 22.

    PMID: 23339874BACKGROUND

  • Milander MM, Hiscok PS, Sanders AB, Kern KB, Berg RA, Ewy GA. Chest compression and ventilation rates during cardiopulmonary resuscitation: the effects of audible tone guidance. Acad Emerg Med. 1995 Aug;2(8):708-13. doi: 10.1111/j.1553-2712.1995.tb03622.x.

    PMID: 7584749BACKGROUND

  • Ochoa FJ, Ramalle-Gomara E, Lisa V, Saralegui I. The effect of rescuer fatigue on the quality of chest compressions. Resuscitation. 1998 Jun;37(3):149-52. doi: 10.1016/s0300-9572(98)00057-4.

    PMID: 9715774BACKGROUND

  • Young KD, Gausche-Hill M, McClung CD, Lewis RJ. A prospective, population-based study of the epidemiology and outcome of out-of-hospital pediatric cardiopulmonary arrest. Pediatrics. 2004 Jul;114(1):157-64. doi: 10.1542/peds.114.1.157.

    PMID: 15231922BACKGROUND

  • Zimmerman E, Cohen N, Maniaci V, Pena B, Lozano JM, Linares M. Use of a Metronome in Cardiopulmonary Resuscitation: A Simulation Study. Pediatrics. 2015 Nov;136(5):905-11. doi: 10.1542/peds.2015-1858. Epub 2015 Oct 12.

    PMID: 26459645DERIVED

MeSH Terms

Conditions

Heart Arrest

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Officials

  • Marc Linares, MD

    Nicklaus Children's Hospital f/k/a Miami Children's Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 22, 2015

First Posted

July 30, 2015

Study Start

October 1, 2013

Primary Completion

July 1, 2014

Study Completion

July 1, 2014

Last Updated

July 30, 2015

Record last verified: 2015-07