NCT02510508

Brief Summary

The aim of this study is to determine whether a group format Community Reinforcement and Family Training (CRAFT) and Self-Directed CRAFT Delivery are more effective than non-intervention in terms of Concerned Significant Others (CSO) well- being and cost- effectiveness.

Trial Health

57
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
29

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2015

Geographic Reach
1 country

6 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 16, 2015

Completed
13 days until next milestone

First Posted

Study publicly available on registry

July 29, 2015

Completed
3 days until next milestone

Study Start

First participant enrolled

August 1, 2015

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2016

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2017

Completed
Last Updated

August 21, 2017

Status Verified

August 1, 2017

Enrollment Period

1.2 years

First QC Date

July 16, 2015

Last Update Submit

August 16, 2017

Conditions

Keywords

addictionsubstance abusealcoholdrugscommunity reinforcementfamily treatmentrandomized control trial

Outcome Measures

Primary Outcomes (1)

  • Concerned Significant Other (CSO) well-being (physical and psychological)

    Measured by the following tests:Measurement of the Addictions for Triage and Evaluation (MATE), Depression Anxiety Scales (DASS-21), Maudsley Addiction Profile (MAP), Research and Development- 36 (RAND- 36), Trimbos/iMTA questionnaire for Costs Associated with Psychiatric Illness (TicP) and EuroQol- 5D.

    4 months after the initiation of the intervention

Secondary Outcomes (4)

  • CSO quality of life

    4 months after the initiation of the intervention

  • CSO quality of the relationship

    4 months after the initiation of the intervention

  • Other CSO reported psychological measures

    4 months after the initiation of the intervention

  • Cost-effectiveness of group CRAFT and Self-Directed CRAFT Delivery compared to non-intervention condition

    4 months after the initiation of the intervention

Other Outcomes (2)

  • Identified Patient (IP) engagement for all three conditions

    4 months after the initiation of the intervention

  • CSO Drop-out

    4 months after the initiation of the intervention

Study Arms (3)

Group CRAFT

EXPERIMENTAL

All CSO's who are allocated to CRAFT group condition will be offered seven sessions of a CRAFT Group format. Each group will meet for 90 minutes weekly and will be completed within 2 months. The group content is based on the CRAFT techniques described by a training manual written by Roozen, Smith and Meyers (2015). Furthermore the CSOs in this condition will also receive a Dutch version of the CRAFT self-help book (Self Directed CRAFT Delivery), "Get your loved one sober: Alternatives to nagging, pleading and threatening" (Meyers \& Wolfe, 2012). Groups will engage in a combination of didactic teaching, role-play of new communication styles and discuss their experiences utilizing CRAFT skills.

Behavioral: Group CRAFTOther: Non-intervention

Self-Directed CRAFT Delivery

ACTIVE COMPARATOR

CSO's allocated to the Self- Directed CRAFT Delivery will receive the Dutch version of the CRAFT self-help book, "Get your loved one sober: Alternatives to nagging, pleading and threatening" (Meyers \& Wolfe, 2012). The book helps CSO's how to utilize the CRAFT model in their daily lives. It includes guidelines for responding to IP behavior, improving positive communication skills, improving the CSO's own well-being and explains how to engage the IP into treatment.

Behavioral: Self-Directed CRAFT DeliveryOther: Non-intervention

Non-intervention

NO INTERVENTION

Participants assigned to the non-intervention condition will be placed on a Group CRAFT waiting list.

Interventions

Group CRAFTBEHAVIORAL

CSOs will receive seven weekly 90 min sessions of CRAFT + Self-Directed CRAFT Delivery

Group CRAFT

CRAFT self-help book (Self Directed CRAFT Delivery)

Also known as: CRAFT self-help book condition
Self-Directed CRAFT Delivery

Non-intervention

Also known as: Waitinglist condition
Group CRAFTSelf-Directed CRAFT Delivery

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • CSO has concern about and having direct knowledge of alcohol- and/or drug problems of an IP, who is either a first degree relative, intimate partner or close friend.
  • Age at least 18 years (the CSO)
  • Reports that IP is not currently in addiction treatment (at IrisZorg and elsewhere) and has not received addiction treatment in the past 3 months
  • Reports that IP is treatment-refusing
  • Evidence (according CSO) that the IP meets criteria for SUDs according to The Structured Clinical Interview for DSM IV axis 1 Disorders (SCID-I)

You may not qualify if:

  • Does not demonstrate an adequate understanding of their participation, informed consent, and requirements of the protocol, or has insufficient reading abilities to comprehend the Dutch self-help book or does not agree to participate by refusing to sign an informed consent
  • CSO meets the DSM-IV criteria for any current SUD diagnosis, through clinical assessment by The Structured Clinical Interview for DSM IV axis 1 Disorders (SCID-I) and the Dutch version of the Mini- International Neuropsychiatric Interview ( M.I.N.I.)
  • Refuses to provide valid locator information, allow audiotaped sessions, and/or participate in follow-ups
  • Evidence that the IP had received treatment (other than detoxification) for alcohol or drug problems in the prior three months, was mandated by the courts to receive treatment, or was currently motivated to accept treatment
  • IP has a recent history of severe domestic violence
  • CSO is involved in a concomitant intervention to get the IP in treatment or to improve their own well-being
  • CSO fails to complete less than 4 Group CRAFT sessions

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

IrisZorg

Arnhem, Gelderland, 6800, Netherlands

Location

IrisZorg

Doetinchem, Gelderland, 7000, Netherlands

Location

IrisZorg

Ede, Gelderland, 6710, Netherlands

Location

IrisZorg

Nijmegen, Gelderland, 6500, Netherlands

Location

IrisZorg

Tiel, Gelderland, 4000, Netherlands

Location

IrisZorg

Zevenaar, Gelderland, 6900, Netherlands

Location

MeSH Terms

Conditions

Behavior, AddictiveSubstance-Related DisordersAlcoholism

Condition Hierarchy (Ancestors)

Compulsive BehaviorImpulsive BehaviorBehaviorChemically-Induced DisordersMental DisordersAlcohol-Related Disorders

Study Officials

  • Hendrik G Roozen, PhD

    University of New Mexico; Department of Psychology/ CASAA

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Ph.D

Study Record Dates

First Submitted

July 16, 2015

First Posted

July 29, 2015

Study Start

August 1, 2015

Primary Completion

October 1, 2016

Study Completion

February 1, 2017

Last Updated

August 21, 2017

Record last verified: 2017-08

Data Sharing

IPD Sharing
Will not share

Locations