NCT02503787

Brief Summary

The purpose of this study is to evaluate programming options in spinal cord stimulation for the management of chronic, intractable pain of the trunk and limbs.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
64

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jul 2015

Geographic Reach
1 country

11 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2015

Completed
13 days until next milestone

First Submitted

Initial submission to the registry

July 14, 2015

Completed
7 days until next milestone

First Posted

Study publicly available on registry

July 21, 2015

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2016

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

September 19, 2017

Completed
Last Updated

September 19, 2017

Status Verified

August 1, 2017

Enrollment Period

1.1 years

First QC Date

July 14, 2015

Results QC Date

July 10, 2017

Last Update Submit

August 17, 2017

Conditions

Keywords

chronic painintractable painfailed back surgery syndrome

Outcome Measures

Primary Outcomes (1)

  • Change in Average Overall Pain as Measured by the Diary-reported Numeric Pain Rating Scale (NPRS) Questionnaire

    Self reported daily average overall pain score 5 days prior to baseline and at 3 months post device activation in subjects receiving programming options in spinal cord stimulation. The question is scored 0-10 (0=no pain; 10=pain as bad as can be).

    From baseline to 3 months post device activation

Secondary Outcomes (1)

  • Patient Global Impression of Change

    From baseline to 3 months post device activation

Other Outcomes (2)

  • Change in Average Back Pain as Measured by the Diary-reported Numeric Pain Rating Scale (NPRS) Questionnaire

    From baseline to 3 months post device activation

  • Change in Average Leg Pain as Measured by the Diary-reported Numeric Pain Rating Scale (NPRS) Questionnaire

    From baseline to 3 months post device activation

Study Arms (1)

Open label treatment

OTHER

Spinal Cord Stimulation (SCS)

Device: Spinal Cord Stimulation (SCS)

Interventions

SCS programming options

Open label treatment

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Candidate for Spinal Cord Stimulation (SCS) system (trial and implant) per labeled indication(back and leg pain)
  • Willing and able to provide a signed and dated informed consent
  • At least 18 years old at the time of informed consent
  • Willing and able to attend visits and comply with the study protocol
  • Capable of using the patient programmer and recharging the neurostimulator
  • Willing to not increase pain medications from baseline through the 3-Month Visit

You may not qualify if:

  • Currently enrolled in or plans to enroll in any concurrent drug and/or device study that may confound study results.
  • Psychological or other health conditions that would interfere with the subject's ability to fulfill the requirements of the protocol.
  • Trialed or implanted with SCS, subcutaneous stimulation, peripheral nerve stimulation or an implantable intrathecal drug delivery system
  • Implanted with a cardiac device (e.g., pacemaker, defibrillator)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (11)

Valley Pain Consultants-North Scottsdale

Scottsdale, Arizona, 85254, United States

Location

Synovation Medical Group

Chula Vista, California, 91914, United States

Location

Center for Interventional Pain Spine

Wilmington, Delaware, 19803, United States

Location

Pain Care LLC

Stockbridge, Georgia, 30281, United States

Location

Millennium Pain Center

Bloomington, Illinois, 61701, United States

Location

The Center for Clinical Research

Winston-Salem, North Carolina, 27103, United States

Location

University Hospitals Case Medical Center

Cleveland, Ohio, 44106-1716, United States

Location

St. Luke's Neurosurgical Associates

Bethlehem, Pennsylvania, 18018, United States

Location

Precision Spine Care

Tyler, Texas, 75701-4262, United States

Location

Swedish Pain Services

Seattle, Washington, 98122, United States

Location

Northwest Pain Care

Spokane, Washington, 99201, United States

Location

MeSH Terms

Conditions

Pain, IntractableChronic PainFailed Back Surgery Syndrome

Interventions

Spinal Cord Stimulation

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsPostoperative ComplicationsPathologic ProcessesBack Pain

Intervention Hierarchy (Ancestors)

Electric Stimulation TherapyTherapeuticsPhysical Therapy ModalitiesRehabilitation

Results Point of Contact

Title
Helen Berrier
Organization
Medtronic Implantable Therapies

Study Officials

  • OPTIONS Clinical Research Study Team

    Medtronic Implantable Therapies

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 14, 2015

First Posted

July 21, 2015

Study Start

July 1, 2015

Primary Completion

August 1, 2016

Study Completion

August 1, 2016

Last Updated

September 19, 2017

Results First Posted

September 19, 2017

Record last verified: 2017-08

Data Sharing

IPD Sharing
Will not share

Locations