Tissue Collection Protocol for Gastroesophageal Cancers
Tissue Collection for Gastro-esophageal Cancer Primary Cell Line Establishment
1 other identifier
observational
100
1 country
1
Brief Summary
This proposed collection of primary tumor cells lines will benefit esophageal cancer research within the University Health Network. This collection of gastro-esophageal tumor samples will be used to grow primary tumor cell lines, which will provide researchers with ready samples of various gastro-esophageal cancers. This will help to address the issue of access to these cell lines due to the limited number of patients with gastro-esophageal tumors, and high rates of contamination.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started May 2015
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2015
CompletedFirst Submitted
Initial submission to the registry
May 27, 2015
CompletedFirst Posted
Study publicly available on registry
July 13, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2030
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 1, 2030
May 14, 2025
May 1, 2025
15.6 years
May 27, 2015
May 13, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Effectively culture, proliferate, and store primary gastro-esophageal cell lines in order to create a bank of primary esophageal / gastric cancers for research purposes
The primary objective of this study is to determine an effective way to culture, proliferate, and store primary gastro-esophageal cell lines in order to create a bank of primary esophageal / gastric cancers or GERD with/without Barrett's esophagus for research purposes, in addition we will be creating organoids.
Ongoing
Study Arms (1)
TIssue Collection
Only one arm will be used to collect tissue from Esophageal Adenocarcinoma
Interventions
Eligibility Criteria
Patients with esophagogastric cancer and/or GERD +/- Barrett's esophagus who will undergo surgery and/or EGD as standard of care.
You may qualify if:
- Patients with esophagogastric cancer and/or GERD +/- Barrett's esophagus who will undergo surgery and/or EGD as standard of care.
You may not qualify if:
- Patients who are not well enough to undergo surgery or EGD as standard of care.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University Health Network: Toronto General Hospital
Toronto, Ontario, M5G 2C4, Canada
Biospecimen
Biopsy Samples
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jonathan Yeung
University Health Network, Toronto
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 27, 2015
First Posted
July 13, 2015
Study Start
May 1, 2015
Primary Completion (Estimated)
December 1, 2030
Study Completion (Estimated)
December 1, 2030
Last Updated
May 14, 2025
Record last verified: 2025-05