NCT02493023

Brief Summary

Bronchoscopic diagnosis and staging of lung cancer must be gentle and quick, and requires optimal sampling precision.Electromagnetic navigation systems are promising for intraoperative guiding based on maps made of preoperative CT images. Navigation accuracy depends largely on correct alignment of preoperative images to the patient´s position in space during endoscopy. In this study, the accuracy of a new fast and automatic image-to-patient registration method during the initial phase of bronchoscopy is assessed in patients referred for lung cancer investigation.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
26

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2011

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2011

Completed
3.8 years until next milestone

First Submitted

Initial submission to the registry

July 1, 2015

Completed
8 days until next milestone

First Posted

Study publicly available on registry

July 9, 2015

Completed
23 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2015

Completed
Last Updated

March 30, 2016

Status Verified

March 1, 2016

Enrollment Period

3.8 years

First QC Date

July 1, 2015

Last Update Submit

March 29, 2016

Conditions

Keywords

BronchoscopyBronchoscopes

Outcome Measures

Primary Outcomes (1)

  • endoscope position (measured in millimetres from origo in the x, y and z-plane) in 3 dimensional maps from preoperative CT images

    intraoperative positional data of bronchoscope or endobronchial ultrasound scope (EBUS) measured and stored in navigation system software, used for registration and navigation system accuracy calculations

    48 hours

Secondary Outcomes (3)

  • duration of procedure

    48 hours

  • patient reported satisfaction

    48 hours

  • adverse events

    48 hours

Study Arms (1)

navigated bronchoscopy

EXPERIMENTAL
Device: navigated bronchoscopy

Interventions

Also known as: position tracked bronchoscope, navigated endobronchial ultrasound (EBUS)
navigated bronchoscopy

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • referred to thoracic department St Olavs Hospital due to suspicion of lung cancer
  • informed consent

You may not qualify if:

  • pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Thoracic Medicine, St Olavs Hospital

Trondheim, Norway

Location

Related Publications (1)

  • Sorger H, Hofstad EF, Amundsen T, Lango T, Leira HO. A novel platform for electromagnetic navigated ultrasound bronchoscopy (EBUS). Int J Comput Assist Radiol Surg. 2016 Aug;11(8):1431-43. doi: 10.1007/s11548-015-1326-7. Epub 2015 Nov 28.

MeSH Terms

Conditions

Bronchial Neoplasms

Condition Hierarchy (Ancestors)

Lung NeoplasmsRespiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsBronchial DiseasesRespiratory Tract Diseases

Study Officials

  • Toril A Nagelhus Hernes, prof

    Department of Circulation and Imaging

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 1, 2015

First Posted

July 9, 2015

Study Start

October 1, 2011

Primary Completion

August 1, 2015

Study Completion

August 1, 2015

Last Updated

March 30, 2016

Record last verified: 2016-03

Locations