NCT02490813|TerminatedDMC
Study Stopped
the study has been on hold throughout 3/10/2020-18/2/2023 due to the hospital regulations for COVID-19
Pilot Study on Traditional Chinese Medicine and Food Allergy
TCMFA
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Sponsor study identifier
interventional
18
1 country
1
Study Start
June 18, 2015
Actual (reported)Primary Completion
February 18, 2023
Actual (reported)Study Completion
February 18, 2023
Actual (reported)Recently, there has been an increasing interest in using traditional Chinese medicine for food allergy. The Harvard group has successfully demonstrated the Food Allergy Herbal Formula - FAHF2 completely blocked peanut-induced anaphylaxis in a murine model, and currently being studied in human. Therefore, in collaboration with the Institute of Chinese Medicine, CUHK, the investigators have developed a more simplified Chinese herbal formula - X (CHFX), containing four food-grade Chinese herbs, Wu-mei (Fructus Pruni Mume); Ling-zhi (Gonoderma); Huang-bai (Cortex Phellodendron) and Zhi-su (Perilla frutescens). In the present study, the investigators would like to examine whether there is reduction in allergic symptoms in food challenge after administering the CHFX for 8 weeks. There will be pre- and post- CHFX food challenges and other related tests.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
February 18, 2023
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Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
June 18, 2015
Actual (reported)July 2, 2015
Actual (reported)July 7, 2015
Actual (reported)February 18, 2023
Actual (reported)February 18, 2023
Actual (reported)Tolerance to existing allergen
subjects will be accessed on tolerance to existing allergen via opened oral food challenge
8 weeks
Skin prick test result
8 weeks
Blood test - IgE result
8 weeks
This arm will receive the placebo.
This arm will receive the Chinese Herbal Formula - CHFX as treatment to their existing fish, shrimp or crab allergy.
Wu Mei (Fructus Pruni Mume), Ling Zhi (Gonoderma), Huang Bai (Cortex Phellodendron), and Zhi Su (Perilla frutescens).
Placebo will be starch with colorings
Hong Kong Sanatorium & Hospital
Happy Valley, Hong Kong
June Chan, Master
Hong Kong Sanatorium & Hospital
18 participants (actual enrollment reported by the registry).
First Submitted
July 2, 2015
First Posted
July 7, 2015
Study Start
June 18, 2015
Actual (reported)Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to confirm eligibility.
Primary Completion
February 18, 2023
Actual (reported)Study Completion
February 18, 2023
Actual (reported)Last Updated
March 1, 2023
Record last verified: 2023-02
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Source: ClinicalTrials.gov.
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