Investigation of the Glycemic Index of Ethiopian Honey

NCT02488018 | Completed Early Phase 1 Results DMC

• 1 other identifier: Honey-1
• Study Type: interventional
• Target: 10
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this study is to determine which of the Ethiopian honeys slowly/rapidly raise the blood glucose level.

Conditions

Hyperglycemia, Postprandial

Keywords

Glycemic index; honey; reference glucose

Outcome Measures

Primary Outcomes (1)

• Examine Effect of Monofloral Honey Types on Glycemic Index of Health Human Subjects

  Ten healthy individuals consumed monofloral honeys (25g of available carbohydrate in 250 mL water) after fasting for 11 hours. Blood glucose levels (mmol/L) were recorded at 0, 15, 30, 45, 60, 90 and 120 minutes. Time (0, 15, 30, 45, 60, 90 and 120 minutes) verse blood glucose levels (mmol/L) used to establish the area under the curve (AUC) for the honeys and reference glucose. This was used to calculate the glycemic index of honey each honey (GI= AUC for honey/AUC for reference glucose\*100). All 10 participants took eight different honeys and reference glucose on nine different days (with randomized allocation of samples).

  36 days (9 tests in 4 days interval)

Study Arms (1)

Provision of experimental honeys

EXPERIMENTAL

Eight experimental monofloral honeys and reference glucose

Biological: Provision of experimental honey

Interventions

Provision of experimental honey BIOLOGICAL

Acacia, Becium grandiflorum, Croton macrostachys, Eucalyptus globules, Hypoestes, Leaucas abyssinica, Schefflera abyssinica, Syzygium guineense and reference glucose were used as test food. 25g available carbohydrate of the test food was provided to ten human subjects after fasted for 11 hours overnight.

Also known as: Honey Glycemic Index

Provision of experimental honeys

Eligibility Criteria

• Age: 20 Years - 24 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Clinical diagnosis of diabetes Disease
• Must be able to drink the honeys and reference glucose

You may not qualify if:

• Overweight, dieting, smoking, a family history of diabetes, pregnant, metabolic disorders, suffering from any illness or food allergy and regularly taking medication.

Sponsors & Collaborators

• Addis Ababa University: lead

MeSH Terms

Conditions

Hyperglycemia

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Results Point of Contact

• Title: Abera Belay (PhD Candidate)
• Organization: Addis Ababa University [Office telephone +251011-655-1927]

ab.berabelay@gmail.com

Mobile +251911840655

Study Officials

• Abera Belay, PhDCandidate

  Addis Ababa University

  PRINCIPAL INVESTIGATOR

• Gulelat Haki, Professor

  Department of Food Science and Technology, Botswana College of Agriculture, University of Botswana.

  STUDY CHAIR

• Kaleab Baye, Asst Prof.

  Addis Ababa University

  STUDY CHAIR

• Samuel Melaku, Assoc Prof.

  Columbus State University

  STUDY CHAIR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: early phase 1
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD Candidate

Study Record Dates

• First Submitted: June 27, 2015
• First Posted: July 2, 2015
• Study Start: June 1, 2015
• Primary Completion: November 1, 2015
• Study Completion: February 1, 2016
• Last Updated: December 28, 2016
• Results First Posted: December 28, 2016

Record last verified: 2016-07