Trials Sponsors Conditions Drugs Pricing

Conditions

Egg Hypersensitivity

Outcome Measures

Primary Outcomes (1)

time to complete egg tolerance
raw egg tolerance (eg in chocolate mousse)
18 to 30 months

Secondary Outcomes (1)

Measurement of specific IgE to egg white components to predict complete egg tolerance
18 to 30 months

Study Arms (2)

Arm 18m

OTHER

arm 18m: 6 months between step 1 and step 2; 6 months between step 2 and step 3, 3 months between all other steps step by step gradual introduction of egg containing food products during 18 months, unless next step can not be taken

Behavioral: shorter or longer period of specific dietary restrictions

arm 30 m

OTHER

arm 30m: 9 months between step 1 and step 2; 9 months between step 2 and step 3, 6 months between all other steps step by step gradual introduction of egg containing food products during 30 months, unless next step can not be taken

Behavioral: shorter or longer period of specific dietary restrictions

Interventions

shorter or longer period of specific dietary restrictionsBehavioral

step by step gradual introduction of egg containing food products

Arm 18marm 30 m

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age12 Months - 18 Years

Sexall

Healthy VolunteersNo

Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

Children (1-18y) had or have a clinical diagnosis of IgE mediated hen's egg allergy based on positive history as well as skin prick testing and/or specific IgE detection by CAPtest in an allergy clinic
Children are at least 12 months old before introduction of heated egg is considered

Sponsors & Collaborators

Dominque Bullens
Otherlead
Algemeen Ziekenhuis Maria Middelares
Othercollaborator
AZ Sint-Jan AV

Study Sites (6)

University Hospital of Leuven

Leuven, Vlaams-Brabant, 3000, Belgium

Imelda Hospital, Bonheiden

Bonheiden, Belgium

Sint-Jan

Bruges, 8000, Belgium

Algemeen Ziekenhuis Maria Middelares

Ghent, Belgium

Jessa Hospital

Hasselt, Belgium

Sint-Jan

Ostend, 8400, Belgium

MeSH Terms

Conditions

Egg Hypersensitivity

Condition Hierarchy (Ancestors)

Food HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Officials

Dominique MA Bullens, MD, PhD
UZ Leuven
PRINCIPAL INVESTIGATOR

Enrollment

86 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: RANDOMIZED
Masking: NONE
Purpose: OTHER
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: SPONSOR INVESTIGATOR
PI Title: MD, PhD

Study Record Dates

First Submitted

June 29, 2015

First Posted

July 1, 2015

Study Start

July 1, 2015

Actual (reported)

Gradual Egg-tolerance Induction in Hen's Egg Allergic Children

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (2)

Arm 18m

arm 30 m

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (6)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (2)

Arm 18m

arm 30 m

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (6)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations