Look at Food and Lose Your Fear - Evaluation of a Computerized Attention Training (CAT) for Anorexia Nervosa Patients
CAT
Evaluation of a Computerized Attention Training (CAT) to Modify Attention Bias for Food Cues in Anorexia Nervosa Patients
1 other identifier
interventional
50
1 country
1
Brief Summary
The purpose of this study is to test the therapeutic effects of a computerized attention training for patients with Anorexia Nervosa (AN). The primary aim is to determine if a computerized attention training can modify attention towards food and ameliorate eating disorder symptoms and related difficulties, such as anxiety. The secondary aim is to explore underlying mechanisms that contribute to these improvements. The stability of potentially observed effects over a one-month period will also be determined.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for phase_1
Started Jun 2015
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2015
CompletedFirst Submitted
Initial submission to the registry
June 25, 2015
CompletedFirst Posted
Study publicly available on registry
June 29, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2016
CompletedJuly 8, 2015
July 1, 2015
1.3 years
June 25, 2015
July 7, 2015
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Attention bias
The dot-probe task with concurrent assessment of eye-movements will be used for the assessment of attention bias at baseline and post-treatment.
max. 2 weeks (pre and post attention bias modification training)
Secondary Outcomes (2)
Eating Disorder symptoms
max. 2 week (pre and post attention bias modification training) and at 4 weeks follow-up
Body Mass Index
max. 2 (pre and post attention bias modification training) and after 4 weeks (follow-up).
Other Outcomes (2)
Eating Behaviour
max. 2 weeks
Approach and avoidance tendencies
max. 2 weeks
Study Arms (2)
CAT active attention bias modification
EXPERIMENTALActive computerized attention training (CAT). Attention training via repeated trials of a modified anti-saccade task with concurrent assessment of eye-movements intended to direct attention towards food stimuli using pictorial food and non-food stimuli (see Werthmann, Field, Roefs, Nederkoorn, \& Jansen, 2014).
CAT sham bias modification
PLACEBO COMPARATORSham computerized attention training. Attention training via repeated trials of a modified anti-saccade task with concurrent assessment of eye-movements not intended to change attention processing of food stimuli using pictures of two different non-food stimuli categories (e.g. household and musical instruments).
Interventions
Three sessions of active computerized attention training.
Three sessions of sham computerized attention training.
Eligibility Criteria
You may qualify if:
- BMI \< 18.5 5 kg/m2
- Current diagnosis of AN-restricting type, AN-Binge/purging type or Eating Disorder Not Otherwise Specified (EDNOS) - Anorexia type
- Fluent in English
You may not qualify if:
- Currently taking a dose of any psychoactive medication that has not been stable for at least 14 days prior to participation in the study
- Currently meeting the diagnostic criteria of another major psychiatric disorder (e.g., major depressive disorder, substance dependence, schizophrenia or bipolar disorder) needing treatment in its own right
- Learning and developmental impairments
- If the disorder is currently life threatening
- If patients are currently suicidal
- If patients are currently having extreme physiological complications or co-morbid alcohol and drug-abuse disorders
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Institute of Psychiatry, Psychology and Neuroscience
London, SE5 8AF, United Kingdom
Related Publications (2)
Neimeijer RA, de Jong PJ, Roefs A. Automatic approach/avoidance tendencies towards food and the course of anorexia nervosa. Appetite. 2015 Aug;91:28-34. doi: 10.1016/j.appet.2015.03.018. Epub 2015 Mar 24.
PMID: 25817483BACKGROUNDWerthmann J, Field M, Roefs A, Nederkoorn C, Jansen A. Attention bias for chocolate increases chocolate consumption--an attention bias modification study. J Behav Ther Exp Psychiatry. 2014 Mar;45(1):136-43. doi: 10.1016/j.jbtep.2013.09.009. Epub 2013 Sep 29.
PMID: 24140811BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jessica Werthmann, PhD
Institute of Psychiatry, Psychology and Neuroscience, King's College London
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- phase 1
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 25, 2015
First Posted
June 29, 2015
Study Start
June 1, 2015
Primary Completion
October 1, 2016
Study Completion
November 1, 2016
Last Updated
July 8, 2015
Record last verified: 2015-07