NCT02477735

Brief Summary

The purpose of this study is to investigate the prevalence of sleep disturbances in children with Chronic Otitis Media with Effusion (COME) and the effect of tympanostomy tube insertion (TTI) on sleep disturbances.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jun 2015

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 21, 2015

Completed
11 days until next milestone

Study Start

First participant enrolled

June 1, 2015

Completed
22 days until next milestone

First Posted

Study publicly available on registry

June 23, 2015

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2017

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2017

Completed
Last Updated

June 23, 2015

Status Verified

May 1, 2015

Enrollment Period

2.2 years

First QC Date

May 21, 2015

Last Update Submit

June 17, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Actigraphy measurements

    Up to two years

Secondary Outcomes (2)

  • OSA-18 questionnaire score

    Up to two years

  • Brief Infant Sleep Questionnaire (BISQ) score

    Up to two years

Study Arms (2)

Study group

Infants with COME who will be referred for TTI will undergo actigraphy for 7 consecutive nights prior to TTI and for 7 consecutive nights 4-6 weeks following TTI.

Device: Actigraphy

Healthy infants

Healthy infants that were recruited from the community well-baby clinics.

Interventions

Actigraphy will be conducted for each participant for 7 consecutive nights prior to TTI and for 7 consecutive nights 4-6 weeks following TTI.

Study group

Eligibility Criteria

Age6 Months - 36 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Infants with COME who will be referred for TTI.

You may qualify if:

  • Age: 6-36 months
  • Referred for tympanostomy tube insertion as a treatment for COME.

You may not qualify if:

  • Snoring and sleep disordered breathing (SDB)
  • Chronic medical condition
  • referred for TTI and adenoidectomy/tonsillectomy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

"DANA" children's hospital

Tel Aviv, Israel

Location

MeSH Terms

Conditions

Parasomnias

Interventions

Actigraphy

Condition Hierarchy (Ancestors)

Sleep Wake DisordersNervous System DiseasesMental Disorders

Intervention Hierarchy (Ancestors)

Monitoring, PhysiologicDiagnostic Techniques and ProceduresDiagnosisAccelerometryInvestigative Techniques

Study Officials

  • Gad Fishman, Doctor

    Dana Children's Hospital, Tel-Aviv Sourasky Medical Center, Sackler School of Medicine Tel-Aviv Univesity, Israel

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Gad Fishman, Doctor

CONTACT

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 21, 2015

First Posted

June 23, 2015

Study Start

June 1, 2015

Primary Completion

August 1, 2017

Study Completion

December 1, 2017

Last Updated

June 23, 2015

Record last verified: 2015-05

Locations