NCT03977545

Brief Summary

The aim of our study is to analyse the correlation between actigraphy and Lipsitz scoring system in neonatal opioid abstinence syndrome.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2019

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 23, 2019

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

June 5, 2019

Completed
1 day until next milestone

First Posted

Study publicly available on registry

June 6, 2019

Completed
2.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2021

Completed
Last Updated

May 3, 2021

Status Verified

April 1, 2021

Enrollment Period

2.9 years

First QC Date

June 5, 2019

Last Update Submit

April 30, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Correlation between actigraphy and Lipsitz scoring system

    Actigraphy and Lipsitz scoring system are realized at the same time twice a day

    ninety minutes after feeding

Study Arms (4)

Newborn with risk of neonatal opioid abstinence syndrome

OTHER

The newborns will have actigraphy during 30 minutes and Lipsitz scoring system twice a day during 7 days

Diagnostic Test: Actigraphy

Eutrophic term newborn

OTHER

The newborns will have actigraphy during 30 minutes and Lipsitz scoring system twice a day during 2 days

Diagnostic Test: Actigraphy

Term newborn with low birth weight

OTHER

The newborns will have actigraphy during 30 minutes and Lipsitz scoring system twice a day during 2 days

Diagnostic Test: Actigraphy

Eutrophic premature newborn

OTHER

The newborns will have actigraphy during 30 minutes and Lipsitz scoring system twice a day during 2 days

Diagnostic Test: Actigraphy

Interventions

ActigraphyDIAGNOSTIC_TEST

Actigraphy will be realized twice a day during 30 minutes and Lipsitz scoring system will be realized at the same moment to analyze the correlation between Lipsitz scoring system and actigraphy in each arm.

Eutrophic premature newbornEutrophic term newbornNewborn with risk of neonatal opioid abstinence syndromeTerm newborn with low birth weight

Eligibility Criteria

AgeUp to 1 Day
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Newborn \> 32 weeks of gestation + 0 day

You may not qualify if:

  • perinatal asphyxia
  • minute Apgar score \< 7
  • ante or post-natal brain injury diagnosis
  • upper arm motor deficit
  • hospitalization in intensive care unit
  • neonatal respiratory distress

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Caen Univerity Hospital

Caen, France

RECRUITING

MeSH Terms

Conditions

Neonatal Abstinence Syndrome

Interventions

Actigraphy

Condition Hierarchy (Ancestors)

Infant, Newborn, DiseasesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesSubstance-Related DisordersChemically-Induced DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Monitoring, PhysiologicDiagnostic Techniques and ProceduresDiagnosisAccelerometryInvestigative Techniques

Central Study Contacts

Elodie LECORPS

CONTACT

Bernard GUILLOIS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 5, 2019

First Posted

June 6, 2019

Study Start

January 23, 2019

Primary Completion

December 31, 2021

Study Completion

December 31, 2021

Last Updated

May 3, 2021

Record last verified: 2021-04

Locations