NCT02475200

Brief Summary

The Phoenix Post-Approval Registry is a prospective, multi-center, single arm registry sponsored by Volcano Corporation to evaluate the short and long term performance and clinical outcomes of the Phoenix Atherectomy System.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2015

Longer than P75 for all trials

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 8, 2015

Completed
2 months until next milestone

First Posted

Study publicly available on registry

June 18, 2015

Completed
3 months until next milestone

Study Start

First participant enrolled

September 14, 2015

Completed
2.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 8, 2018

Completed
2.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

May 29, 2020

Completed
Last Updated

June 9, 2020

Status Verified

June 1, 2020

Enrollment Period

2.6 years

First QC Date

April 8, 2015

Last Update Submit

June 5, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Phoenix device performance

    Rates of TECHNICAL SUCCESS (ratio of Phoenix treated lesions with \<=50% residual diameter stenosis to all Phoenix treated lesions); and PROCEDURAL SUCCESS (ratio of target lesion residual stenosis of \<=30% after treatment with Phoenix and adjunctive treatments to all treated lesions)

    30 days

Secondary Outcomes (7)

  • Ankle brachial index (ABI)

    12 months

  • Society for Vascular Surgery's Wound, Ischemia, and foot Infection (WIfI) category

    12 months

  • Rutherford Clinical Category

    12 months

  • Clinically-driven target vessel revascularization (TVR) in patients with CLI at baseline

    12 months

  • Clinically-driven target lesion revascularization (TLR) in patients with CLI at baseline

    12 months

  • +2 more secondary outcomes

Interventions

Selectively cut and remove atheromatous plaque in the lower extremities. Debulking and removal of atherosclerotic burden plaque with Phoenix Atherectomy System.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

This study will include patients who are scheduled to receive atherectomy with the Phoenix Atherectomy System used according to local standards.

You may qualify if:

  • The patient is ≥18 years of age.
  • Patient understands the research nature of the study and is willing and capable of providing written informed consent.
  • Scheduled for and receives treatment with the Phoenix Atherectomy System as all or part of their PAD treatment.
  • Meets Phoenix Atherectomy System catheter Instruction for Use (IFU) criteria.

You may not qualify if:

  • Patients unwilling or unable to comply with the protocol including 12-month follow-up for patients with CLI at baseline.
  • Patient is participating in another device or drug clinical trial that interferes with this protocol follow up schedule.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Pima Vascular

Tucson, Arizona, 85718, United States

Location

St. John Hospital

Detroit, Michigan, 48236, United States

Location

Mid-Michigan Heart & Vascular Center

Saginaw, Michigan, 48604, United States

Location

Jackson Heart Clinic

Jackson, Mississippi, 39216, United States

Location

Cardiovascular Specialists of Texas

Austin, Texas, 78758, United States

Location

MeSH Terms

Conditions

Peripheral Arterial DiseaseIntermittent ClaudicationChronic Limb-Threatening Ischemia

Interventions

Atherectomy

Condition Hierarchy (Ancestors)

AtherosclerosisArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCardiovascular DiseasesPeripheral Vascular DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsChronic DiseaseDisease AttributesPathologic ProcessesIschemia

Intervention Hierarchy (Ancestors)

AngioplastyCatheterizationTherapeuticsEndovascular ProceduresVascular Surgical ProceduresCardiovascular Surgical ProceduresSurgical Procedures, OperativeMinimally Invasive Surgical ProceduresInvestigative Techniques

Study Officials

  • Bradley S Matsubara, MD

    Volcano Corporation

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Target Duration
12 Months
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 8, 2015

First Posted

June 18, 2015

Study Start

September 14, 2015

Primary Completion

April 8, 2018

Study Completion

May 29, 2020

Last Updated

June 9, 2020

Record last verified: 2020-06

Locations