NCT02460029

Brief Summary

The aim of this study is the visualization of the mesh surface and the confirmation with MRI scan at 1 month and 13 months after standardized retromuscular incisional hernia repair with the visible CICAT mesh (Dynamesh®).

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
10

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started May 2015

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2015

Completed
25 days until next milestone

First Submitted

Initial submission to the registry

May 26, 2015

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 2, 2015

Completed
6.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2021

Completed
Last Updated

January 20, 2021

Status Verified

January 1, 2021

Enrollment Period

6.6 years

First QC Date

May 26, 2015

Last Update Submit

January 18, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • visualization of the mesh surface

    Clear visualization of the CICAT® prosthesis at 1 month postoperatively with MRI

    1 month

Secondary Outcomes (2)

  • calculation of the mesh surface

    up to 13 months

  • visualization of the mesh surface

    up to 13 months

Interventions

Visualization of the mesh surface and the confirmation with MRI scan at 1 month and 13 months after standardized retromusculare incisional hernia repair with the visible CICAT mesh (Dynamesh®).

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult patients scheduled for an open retromusculare repair of an incisional hernia.

You may qualify if:

  • patients scheduled for an retromusculare repair of an incisional hernia

You may not qualify if:

  • \<18 years
  • Emergency surgery (incarcerated hernia)
  • Clean-contaminated or contaminated procedures
  • ASA score\> 4
  • Pregnancy
  • No patient Informed Consent
  • Life expectancy of less than 2 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

AZ Maria Middelares

Ghent, 9000, Belgium

RECRUITING

Related Publications (3)

  • Hansen NL, Ciritsis A, Otto J, Busch D, Kuhl CK, Kraemer NA. Utility of Magnetic Resonance Imaging to Monitor Surgical Meshes: Correlating Imaging and Clinical Outcome of Patients Undergoing Inguinal Hernia Repair. Invest Radiol. 2015 Jul;50(7):436-42. doi: 10.1097/RLI.0000000000000148.

    PMID: 25756683BACKGROUND
  • Ciritsis A, Hansen NL, Barabasch A, Kuehnert N, Otto J, Conze J, Klinge U, Kuhl CK, Kraemer NA. Time-dependent changes of magnetic resonance imaging-visible mesh implants in patients. Invest Radiol. 2014 Jul;49(7):439-44. doi: 10.1097/RLI.0000000000000051.

  • Hansen NL, Barabasch A, Distelmaier M, Ciritsis A, Kuehnert N, Otto J, Conze J, Klinge U, Hilgers RD, Kuhl CK, Kraemer NA. First in-human magnetic resonance visualization of surgical mesh implants for inguinal hernia treatment. Invest Radiol. 2013 Nov;48(11):770-8. doi: 10.1097/RLI.0b013e31829806ce.

MeSH Terms

Conditions

HerniaRecurrence

Condition Hierarchy (Ancestors)

Pathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsDisease AttributesPathologic Processes

Study Officials

  • Filip Muysoms, MD. PhD

    Algemeen Ziekenhuis Maria Middelares

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Filip Muysoms, MD, PhD

CONTACT

Iris Kyle-Leinhase, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Head of the Department of Surgery

Study Record Dates

First Submitted

May 26, 2015

First Posted

June 2, 2015

Study Start

May 1, 2015

Primary Completion

December 1, 2021

Study Completion

December 1, 2021

Last Updated

January 20, 2021

Record last verified: 2021-01

Data Sharing

IPD Sharing
Will not share

Locations