Effects of Mirror Therapy Combined With Progressive Strength Training in Unilateral Spastic Cerebral Palsy

NCT02458612 | Completed

• 1 other identifier: GO 15/135-43
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to investigate the effects of mirror therapy combined with upper extremity strengthening training on upper extremity function in children with unilateral spastic Cerebral Palsy (CP): a single blind randomized controlled trial. In the literature, there was no randomized controlled trial. According to literature, there are few studies that investigate the effects of mirror therapy in children with CP. But there is no randomized controlled trial, explore the effects of mirror therapy combined with upper extremity strength training on upper extremity functions in unilateral spastic CP. Hypothesis of this study is that mirror therapy combined with strength training improves upper extremity function and muscle strength in unilateral spastic CP.

Conditions

Spastic Hemiplegic Cerebral Palsy

Keywords

cerebral palsy; mirror therapy; strength training

Outcome Measures

Primary Outcomes (1)

• upper extremity skills

  Quality of upper extremity skills assessment will be assessed by Quality of Upper Extremity Skills Test (QUEST). The test evaluates that handcraft and the quality of the movement in children with CP. It examines the quality of upper extremity skills in 5 sub-sections. It is used to between 18 monhts- 8 years age of children.

  change from baseline upper extremity skills at 12 weeks

Secondary Outcomes (2)

• muscle tone

  change from baseline muscle tone at 12 weeks

• muscle strength

  change from baseline muscle stregth at 12 weeks

Study Arms (2)

control group

OTHER

We will apply only upper limbs exercises with traditional therapy.

Other: control group

intervention group

ACTIVE COMPARATOR

We will apply mirror therapy and progressive strength training for upper extremities.

Other: intervention group

Interventions

control group OTHER

We will apply traditional physiotherapy including upper limb exercises in three times a week for 12 week.

Also known as: traditional therapy

control group

intervention group OTHER

Participants allocated to the experimental group completed three times a week, 12-week mirror therapy combined with progressive strength training. This protocol consisted of mirror therapy with a mirror box, strength training with Thera-band and exercises for scapular dyskinesis. This intensity of training is approximately equal to training at an intensity of 60% to 80% of one-repetition maximum according to "National Strength and Conditioning Association (NSCA)" protocols. Intensity of exercise is gradually increased 10% bi-weekly.

Also known as: mirror therapy and progressive strength training

intervention group

Eligibility Criteria

• Age: 6 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• age between 6 years and 18 years
• classified in levels I or II of the Gross Motor Function Classification System (GMFCS)
• classified in levels I, II-III of the Manual Ability Classification System (MACS)
• able to follow and accept verbal instructions.

You may not qualify if:

• any orthopaedic surgery or botulinum toxin injection in the past 6 months,
• children whose parents refused to participate
• Epileptic seizures that can not be stopped
• Individuals who can not participate in any physical activities because of chronic disease except cerebral palsy.

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Hacettepe University

Ankara, 06100, Turkey (Türkiye)

Location

Related Publications (3)

• Gygax MJ, Schneider P, Newman CJ. Mirror therapy in children with hemiplegia: a pilot study. Dev Med Child Neurol. 2011 May;53(5):473-6. doi: 10.1111/j.1469-8749.2011.03924.x. Epub 2011 Mar 17.

  PMID: 21410693 BACKGROUND

• Piraua AL, Pitangui AC, Silva JP, Pereira dos Passos MH, Alves de Oliveira VM, Batista Lda S, Cappato de Araujo R. Electromyographic analysis of the serratus anterior and trapezius muscles during push-ups on stable and unstable bases in subjects with scapular dyskinesis. J Electromyogr Kinesiol. 2014 Oct;24(5):675-81. doi: 10.1016/j.jelekin.2014.05.009. Epub 2014 Jun 12.

  PMID: 24997890 BACKGROUND

• Rameckers EA, Janssen-Potten YJ, Essers IM, Smeets RJ. Efficacy of upper limb strengthening in children with Cerebral Palsy: A critical review. Res Dev Disabil. 2015 Jan;36C:87-101. doi: 10.1016/j.ridd.2014.09.024. Epub 2014 Oct 15.

  PMID: 25462469 BACKGROUND

MeSH Terms

Conditions

Cerebral Palsy

Interventions

Control Groups; Mirror Movement Therapy

Condition Hierarchy (Ancestors)

Brain Damage, Chronic; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Intervention Hierarchy (Ancestors)

Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods; Physical Therapy Modalities; Rehabilitation; Therapeutics

Study Officials

• Ozgun Kaya Kara, PhD

  Hacettepe University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PT, PhD

Study Record Dates

• First Submitted: May 28, 2015
• First Posted: June 1, 2015
• Study Start: June 1, 2016
• Primary Completion: November 1, 2016
• Study Completion: December 1, 2017
• Last Updated: February 12, 2020

Record last verified: 2020-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)