NCT02451319

Brief Summary

To compare the safety and Efficiency of 20w 30w holmium laser device in treatment of 1-2 cm diameter kidney stones with Retrograde Intrarenal Surgery (RIRS).

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
90

participants targeted

Target at P50-P75 for phase_4

Timeline
Completed

Started Jan 2015

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2015

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

April 28, 2015

Completed
23 days until next milestone

First Posted

Study publicly available on registry

May 21, 2015

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2017

Completed
Last Updated

May 21, 2015

Status Verified

May 1, 2015

Enrollment Period

1.9 years

First QC Date

April 28, 2015

Last Update Submit

May 20, 2015

Conditions

Keywords

RIRS, holmium, 1-2 cm,stones,kidney

Outcome Measures

Primary Outcomes (2)

  • Safety - complications according to clavien system

    complications according to clavien system

    postoperative 24 hours

  • safety - visual analog score

    visual analog score

    postoperative 24 hours

Secondary Outcomes (1)

  • efficiency - stone free rate

    postoperative 24 hours

Study Arms (3)

first group

ACTIVE COMPARATOR

Patients undergoing Retrograde Intrarenal Surgery with 20w holmium laser device who have 1-2 cm diameter kidney stones

Procedure: Retrograde Intrarenal Surgery

second group

ACTIVE COMPARATOR

Patients undergoing Retrograde Intrarenal Surgery with 30w holmium laser device (working over 20w power) who have 1-2 cm diameter kidney stones

Procedure: Retrograde Intrarenal Surgery

third group

ACTIVE COMPARATOR

Patients undergoing Retrograde Intrarenal Surgery with 30w holmium laser(working under 20w power) device who have 1-2 cm diameter kidney stones

Procedure: Retrograde Intrarenal Surgery

Interventions

Endoscopic treatment of Kidney Stones

first groupsecond groupthird group

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients who are between 18-90 years old
  • Patients undergoing RIRS for treatment of 1-2 cm diameter kidney stones

You may not qualify if:

  • Patients who have congenital urogenital abnormalities
  • Patients who have previous stone surgery history

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tuekey Ministry of HealthDıskapı Yıldırım Beyazıt Training and Research Hospital

Ankara, 06110, Turkey (Türkiye)

RECRUITING

Related Publications (1)

  • Redondo C, Ramon de Fata F, Gimbernat H, Meilan E, Andres G, Angulo JC. Retrograde intrarenal surgery with holmium-YAG laser lithotripsy in the primary treatment of renal lithiasis. Actas Urol Esp. 2015 Jun;39(5):320-6. doi: 10.1016/j.acuro.2014.06.004. Epub 2014 Oct 25. English, Spanish.

MeSH Terms

Conditions

Nephrolithiasis

Condition Hierarchy (Ancestors)

Kidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesUrolithiasisMale Urogenital Diseases

Study Officials

  • Nihat Karakoyunlu, MD

    Dıskapı TRH

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Nihat Karakoyunlu, MD

CONTACT

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

April 28, 2015

First Posted

May 21, 2015

Study Start

January 1, 2015

Primary Completion

December 1, 2016

Study Completion

January 1, 2017

Last Updated

May 21, 2015

Record last verified: 2015-05

Locations