Intermountain INSPIRE Registry

NCT02450006 | Recruiting

• 1 other identifier: 1024811
• Study Type: observational
• Target: 50,000
• Locations: 1 country
• Sites: 1

Brief Summary

To collect biological samples, clinical information and laboratory data from patients diagnosed with any healthcare-related conditions who are seen at facilities affiliated with Intermountain Healthcare, including patients and their family members, and to collect the same information and samples from a general population including disease-free subjects.

Conditions

Condition

Outcome Measures

Primary Outcomes (1)

• All-cause mortality

  10 years

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients diagnosed with any healthcare-related conditions who are seen at facilities affiliated with Intermountain Healthcare, including patients and their family members, the general population, including disease-free subjects.

You may qualify if:

• Males or females of any age, any ethnicity, diagnosed with any healthcare-related conditions, presenting to an Intermountain Healthcare-affiliated facility or males or females of any age, any ethnicity, with or without any healthcare-related conditions, including disease-free subjects, from a general population that may include unaffected family members
• Patient or patient's representative has the ability to understand and sign a written informed consent form, which must be obtained prior to initiation of any study procedures, using a form that is approved by the applicable IRB.

You may not qualify if:

• Inability or refusal of the patient and/or the patient's legally-acceptable representative to provide informed consent for any reason.
• Other conditions that in the opinion of the Principal Investigator or Co-Investigator(s) may increase risk to the subject and/or compromise the quality of the registry project.

Sponsors & Collaborators

• Intermountain Health Care, Inc.: lead

Study Sites (1)

Intermountain Medical Center and Intermountain Clinics

Murray, Utah, 84143, United States

RECRUITING

Related Publications (2)

• Horne BD, May HT, Muhlestein JB, Le VT, Bair TL, Knowlton KU, Anderson JL. Association of periodic fasting with lower severity of COVID-19 outcomes in the SARS-CoV-2 prevaccine era: an observational cohort from the INSPIRE registry. BMJ Nutr Prev Health. 2022 Jul 1;5(2):145-153. doi: 10.1136/bmjnph-2022-000462. eCollection 2022 Dec.

  PMID: 36619318 DERIVED

• Bartholomew CL, Muhlestein JB, Anderson JL, May HT, Knowlton KU, Bair TL, Le VT, Bailey BW, Horne BD. Association of periodic fasting lifestyles with survival and incident major adverse cardiovascular events in patients undergoing cardiac catheterization. Eur J Prev Cardiol. 2022 Jan 11;28(16):1774-1781. doi: 10.1093/eurjpc/zwaa050.

  PMID: 33624026 DERIVED

Biospecimen

Retention: SAMPLES WITH DNA

Examples of the biological samples that may be collected are as follows (but not limited to): * Blood/Plasma * Bone Marrow * Buccal smear (cheek) * Cartilage * Cerebrospinal fluid * Mucus * Saliva * Sputum * Stool * Sweat * Synovial fluid * Tears * Tissue samples (e.g. muscle, skin, nails, tumor, etc) * Urine * Seminal fluid * Genetic material extracted from any biological sample * Other biological samples as identified by the Principal Investigator or Co-Investigators and agreed by the patient.

MeSH Terms

Conditions

Disease

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Joseph B Muhlestein, MD

CONTACT

801-507-4701; brent.muhlestein@imail.org

Patti Spencer

CONTACT

801-507-4778; patti.spencer@imail.org

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: PROSPECTIVE
• Target Duration: 50 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 20, 2015
• First Posted: May 21, 2015
• Study Start: April 1, 2015
• Primary Completion (Estimated): April 1, 2050
• Study Completion (Estimated): April 1, 2050
• Last Updated: April 14, 2026

Record last verified: 2026-04

Locations

US (1)