Evaluation of Conditional Cash Transfers to Increase Retention in PMTCT Services in Akwa Ibom State, Nigeria

NCT02447159 | Completed

• 1 other identifier: CCT for PMTCT
• Study Type: interventional
• Target: 554
• Locations: 1 country
• Sites: 3

Brief Summary

A randomized controlled trial will be conducted to assess the effectiveness of conditional cash transfers (CCTs) at increasing retention in prevention of mother-to-child transmission (PMTCT) services specifically, in relation to pickup of ARV drugs for infected mothers, delivery in the hospital setting, and receipt of drugs for exposed infants. Administrative data will be extracted from the All Babies are Equal program and hospital records. At 8-10 weeks after delivery, an endline survey will also be conducted with each participant to provide a deeper understanding of the impact of the CCTs and to assess the reasons for retention in PMTCT services.

Conditions

HIV; HIV Infections; Pregnancy; Infant, Newborn, Diseases

Keywords

Nigeria; Developing Countries; Hospitals, Maternity/Utilization; Hospitals/Economics; HIV

Outcome Measures

Primary Outcomes (2)

• Number and percentage of pregnant women who deliver their baby at the facility in which they were first enrolled for antenatal care

  When the woman delivers her child

• Number and percentage of mothers who obtain early infant diagnosis testing 6-8 weeks after giving birth to their child

  6-8 weeks after the woman delivers her child

Secondary Outcomes (2)

• Number and percentage of pregnant women who pick up their antiretroviral treatment drugs at least once between enrolling in antenatal care and giving birth to their baby at the facility where they first enrolled in antenatal care

  Between enrollment into antenatal care until the woman delivers her child

• Number and percentage of mothers who pick up Nevirapine for their newborn infant at the facility where they first enrolled in antenatal care after giving birth

  48 hours after the woman delivers her child

Study Arms (2)

Intervention

EXPERIMENTAL

Each participant in the intervention arm will receive conditional cash transfers when she: (1) registers pregnancy, (2)picks up her medication in the first two months after her first visit, (3) delivers at the health clinic, and (4) receives early infant diagnosis test for newborn. Eight to ten weeks after delivery, the participant will also be asked to participate in an endline survey and will be compensated for her time.

Behavioral: Conditional Cash Transfers

Control

NO INTERVENTION

Antenatal care utilization data will be extracted from the administrative records. Eight to ten weeks after delivery, the participant will also be asked to participate in an endline survey and will be compensated for her time.

Interventions

Conditional Cash Transfers BEHAVIORAL

Each participant in the intervention arm will receive conditional cash transfers when she: (1) registers pregnancy, (2)picks up her medication in the first two months after her first visit, (3) delivers at the health clinic, and (4) receives early infant diagnosis test for newborn. Eight to ten weeks after delivery, the participant will also be asked to participate in an endline survey and will be compensated for her time.

Intervention

Eligibility Criteria

• Age: 15 Years - 45 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• HIV positive
• Pregnant
• Attended an antenatal care visit at one of three participating clinics.

You may not qualify if:

• Not HIV positive
• Not pregnant
• Not registered for antenatal care at a participating clinic.

Sponsors & Collaborators

• University of California, San Francisco: lead
• University of California, Berkeley: collaborator
• New Incentives: collaborator
• Bill and Melinda Gates Foundation: collaborator

Study Sites (3)

Immanuel General Hospital

Eket, Akwa Ibom State, Nigeria

Location

General Hospital, Ikot Ekpene

Ikot Ekpene, Akwa Ibom State, Nigeria

Location

General Hospital, Iquita Oron

Oron, Akwa Ibom State, Nigeria

Location

Related Publications (7)

• Sturt AS, Dokubo EK, Sint TT. Antiretroviral therapy (ART) for treating HIV infection in ART-eligible pregnant women. Cochrane Database Syst Rev. 2010 Mar 17;2010(3):CD008440. doi: 10.1002/14651858.CD008440.

  PMID: 20238370 BACKGROUND

• de Walque D, Dow WH, Nathan R, Abdul R, Abilahi F, Gong E, Isdahl Z, Jamison J, Jullu B, Krishnan S, Majura A, Miguel E, Moncada J, Mtenga S, Mwanyangala MA, Packel L, Schachter J, Shirima K, Medlin CA. Incentivising safe sex: a randomised trial of conditional cash transfers for HIV and sexually transmitted infection prevention in rural Tanzania. BMJ Open. 2012 Feb 8;2(1):e000747. doi: 10.1136/bmjopen-2011-000747. Print 2012.

  PMID: 22318666 BACKGROUND

• Pettifor A, MacPhail C, Nguyen N, Rosenberg M. Can money prevent the spread of HIV? A review of cash payments for HIV prevention. AIDS Behav. 2012 Oct;16(7):1729-38. doi: 10.1007/s10461-012-0240-z.

  PMID: 22760738 BACKGROUND

• Glassman A, Duran D, Fleisher L, Singer D, Sturke R, Angeles G, Charles J, Emrey B, Gleason J, Mwebsa W, Saldana K, Yarrow K, Koblinsky M. Impact of conditional cash transfers on maternal and newborn health. J Health Popul Nutr. 2013 Dec;31(4 Suppl 2):48-66.

  PMID: 24992803 BACKGROUND

• Baird SJ, Garfein RS, McIntosh CT, Ozler B. Effect of a cash transfer programme for schooling on prevalence of HIV and herpes simplex type 2 in Malawi: a cluster randomised trial. Lancet. 2012 Apr 7;379(9823):1320-9. doi: 10.1016/S0140-6736(11)61709-1. Epub 2012 Feb 15.

  PMID: 22341825 BACKGROUND

• Lim SS, Dandona L, Hoisington JA, James SL, Hogan MC, Gakidou E. India's Janani Suraksha Yojana, a conditional cash transfer programme to increase births in health facilities: an impact evaluation. Lancet. 2010 Jun 5;375(9730):2009-23. doi: 10.1016/S0140-6736(10)60744-1.

  PMID: 20569841 BACKGROUND

• Liu JX, Shen J, Wilson N, Janumpalli S, Stadler P, Padian N. Conditional cash transfers to prevent mother-to-child transmission in low facility-delivery settings: evidence from a randomised controlled trial in Nigeria. BMC Pregnancy Childbirth. 2019 Jan 16;19(1):32. doi: 10.1186/s12884-019-2172-3.

  PMID: 30651080 DERIVED

MeSH Terms

Conditions

HIV Infections; Infant, Newborn, Diseases; Patient Acceptance of Health Care

Condition Hierarchy (Ancestors)

Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Treatment Adherence and Compliance; Health Behavior; Behavior

Study Officials

• Jenny Liu, PhD, MPP

  University of California, San Francisco

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Economist

Study Record Dates

• First Submitted: May 7, 2015
• First Posted: May 18, 2015
• Study Start: August 1, 2015
• Primary Completion: March 1, 2017
• Study Completion: April 1, 2017
• Last Updated: May 3, 2017

Record last verified: 2017-05

Locations

NG (3)