Key Highlights

Risk & Performance

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

5.5%

25 terminated/withdrawn out of 456 trials

Success Rate

92.6%

+6.1% vs industry average

Late-Stage Pipeline

27%

123 trials in Phase 3/4

Results Transparency

18%

57 of 312 completed trials have results

Key Signals

31 recruiting57 with results16 terminated9 withdrawn

Enrollment Performance

Analytics

N/A

156(40.2%)

Phase 3

73(18.8%)

Phase 2

60(15.5%)

Phase 4

50(12.9%)

Phase 1

48(12.4%)

Early Phase 1

1(0.3%)

388Total

N/A(156)

Phase 3(73)

Phase 2(60)

Phase 4(50)

+2 more

Activity Timeline

Global Presence

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Clinical Trials (456)

Showing 20 of 456 trials

NCT05119166Active Not Recruiting

International Milk Composition (IMiC) Consortium

Role: collaborator

NCT06694753Phase 1Recruiting

Safety and Immunogenicity Study of Three mRNAs Encoding HIV Immunogens in Adult Participants Without HIV and in Overall Good Health in South Africa.

Role: collaborator

NCT07566754Phase 2Not Yet Recruiting

MOTIF@FRESH: Modifying Organisms Transvaginally in Females @ FRESH

Role: collaborator

NCT02968849Phase 2Completed

Pivotal Phase 2b/3 ALVAC/Bivalent gp120/MF59 HIV Vaccine Prevention Safety and Efficacy Study in South Africa

Role: collaborator

NCT07229261Not ApplicableRecruiting

MitoQ to Improve Vascular Funciton in Preeclampsia

Role: collaborator

NCT07558122Phase 1Not Yet Recruiting

Malaria CVD 36000; Gates INV090205

Role: collaborator

NCT06062238Phase 3Active Not Recruiting

Study to Assess Efficacy and Safety of M72/AS01E-4 Mycobacterium Tuberculosis (Mtb) Vaccine in Adolescents and Adults

Role: collaborator

NCT04381936Phase 3Recruiting

Randomised Evaluation of COVID-19 Therapy

Role: collaborator

NCT06320535Phase 1Active Not Recruiting

A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™

Role: collaborator

NCT05174884Phase 1Active Not Recruiting

Casea S Contraceptive Implants (Casea S) Trial

Role: collaborator

NCT07439003Recruiting

Behavioral Risk Identification and Decision Guidance for HIV Engagement

Role: collaborator

NCT07428577Recruiting

Tracking and Continuity of Care in Advanced HIV Disease

Role: collaborator

NCT04235816Phase 3Active Not Recruiting

Improving Care Through Azithromycin Research for Infants in Africa

Role: collaborator

NCT07489664Not ApplicableNot Yet Recruiting

Indigenous Nutritional Supplements for Pregnancy to Improve Resilience in Environmental Heat

Role: collaborator

NCT05373758Not ApplicableRecruiting

A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure on TLD in Sub-Saharan Africa

Role: collaborator

NCT05500482Phase 4Completed

Vellore Typhoid Vaccine Impact Trial

Role: collaborator

NCT06050356Phase 1Active Not Recruiting

First-in-Human Trial of the Novel Tuberculosis Vaccine Candidate, H107e/CAF®10b

Role: collaborator

NCT06485258Phase 1Completed

CDC-9 Inactivated Rotavirus Vaccine (IRV) Intramuscular (IM) Phase 1 Clinical Trial in Healthy Adults

Role: collaborator

NCT02738892Active Not Recruiting

Zambian Preterm Birth Prevention Study

Role: collaborator

NCT00148629Phase 3Completed

Treatment and Prevention of Severe Anemia in Pregnant Zanzibari Women

Role: collaborator