NCT02444832

Brief Summary

Based on the anatomical features of the anterior Communicating artery complex, the investigators will analyze the outcome of the ACoA aneurysms treated by endovascular therapy. The most common site of intracranial aneurysms is the anterior communicating artery (AcomA). AcomA aneurysms account for approximately one-fourth of all intracranial aneurysms. Recent publications have addressed specifically the endovascular treatment of AcoA aneurysms. Furthermore, detailed anatomic characteristics and the effects of the multiple variations of the anterior communicating artery complex have scarcely been reported. The hemodynamic factors play a fundamental role in the adequate treatment of aneurismal coiling. The objective of our registry is to analyze the impact of morphological configuration of the anterior communicating artery complex and the results of coil embolization in AcoA aneurysms

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2015

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2015

Completed
11 days until next milestone

First Submitted

Initial submission to the registry

May 12, 2015

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 15, 2015

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2017

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2017

Completed
Last Updated

May 15, 2015

Status Verified

May 1, 2015

Enrollment Period

2.1 years

First QC Date

May 12, 2015

Last Update Submit

May 14, 2015

Conditions

Intracranial AneurysmAnterior Communicating Artery AneurysmCerebral AneurysmAneurysm, Ruptured

Outcome Measures

Primary Outcomes (1)

  • Effective Aneurysm Coiling (no residual cerebral aneurysm)

    1 year

Secondary Outcomes (3)

  • All Cause Mortality

    1 year

  • Neurological Outcome (classified with the Glasgow Outcome Scale, Rankin Scale)

    1 year

  • Procedural device-related serious adverse events

    1 year

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with Communicating Artery Aneurysm treated with endovascular coiling.

You may qualify if:

  • Patient with Anterior Communicating Artery Aneurysm treated with endovascular coiling.

You may not qualify if:

  • Patients without imaging follow up of at least 12 months after endovascular treatment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital Clinic

Barcelona, Barcelona, 08036, Spain

RECRUITING

Related Publications (4)

  • Elias T, Ogungbo B, Connolly D, Gregson B, Mendelow AD, Gholkar A. Endovascular treatment of anterior communicating artery aneurysms: results of clinical and radiological outcome in Newcastle. Br J Neurosurg. 2003 Jun;17(3):278-86. doi: 10.1080/0268869031000153251.

    PMID: 14565533BACKGROUND

  • Moret J, Pierot L, Boulin A, Castaings L, Rey A. Endovascular treatment of anterior communicating artery aneurysms using Guglielmi detachable coils. Neuroradiology. 1996 Nov;38(8):800-5. doi: 10.1007/s002340050352.

    PMID: 8957810BACKGROUND

  • Birknes JK, Hwang SK, Pandey AS, Cockroft K, Dyer AM, Benitez RP, Veznedaroglu E, Rosenwasser RH. Feasibility and limitations of endovascular coil embolization of anterior communicating artery aneurysms: morphological considerations. Neurosurgery. 2006 Jul;59(1):43-52; discussion 43-52. doi: 10.1227/01.NEU.0000219220.25721.B9.

    PMID: 16823299BACKGROUND

  • Molyneux AJ, Kerr RS, Yu LM, Clarke M, Sneade M, Yarnold JA, Sandercock P; International Subarachnoid Aneurysm Trial (ISAT) Collaborative Group. International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion. Lancet. 2005 Sep 3-9;366(9488):809-17. doi: 10.1016/S0140-6736(05)67214-5.

    PMID: 16139655BACKGROUND

MeSH Terms

Conditions

Intracranial AneurysmAneurysm, Ruptured

Condition Hierarchy (Ancestors)

Intracranial Arterial DiseasesCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesAneurysmVascular DiseasesCardiovascular Diseases

Study Officials

  • Federico Zarco, MD

    Hospital Clinic of Barcelona

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Federico Zarco, MD

CONTACT

932275400fzarco@clinic.ub.es

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Neurorradiologist,

Study Record Dates

First Submitted

May 12, 2015

First Posted

May 15, 2015

Study Start

May 1, 2015

Primary Completion

June 1, 2017

Study Completion

December 1, 2017

Last Updated

May 15, 2015

Record last verified: 2015-05

Locations

ES(1)