Prevalence and Factors Associated With the Occurrence of Depression Six Months After an Endovascular Treatment of Intracranial Aneurysm

NCT02866812 | Completed

• 1 other identifier: PA15099
• Study Type: interventional
• Target: 133
• Locations: 1 country
• Sites: 1

Brief Summary

During the last decade, the embolization has become the treatment of choice for ruptured intracranial aneurysms, to improve the neurological outcome of patients. At the same time, for his safety, she also became the technique allowing prophylactic treatment of unruptured intracranial aneurysms discovered incidentally during imaging exams. Regarding patients with ruptured intracranial aneurysms, patients who survive often have a reduced quality of life while one in two has a good neurological outcome after embolization. Depression, anxiety and fatigue, whose the psycho-social impact is important, are often cited. This description has often been done without considering the realized type of treatment (surgery or embolization) and mostly of neurological and functional status of the patient remotely (disability or not in daily activities). Regarding patients with unruptured intracranial aneurysms, they are mostly asymptomatic and embolization is programmed. They would present an cognitive impairment in one case in five at 1 month of treatment. If depression, fatigue and difficult return to working life are logically found in patients with severe sequelae (disability in daily activities) of their ruptured intracranial aneurysms, the question arises for patients with a ruptured intracranial aneurysms with a favorable evolution and for asymptomatic patients with unruptured intracranial aneurysms. A precise status of these populations is necessary, especially as the discovery and treatment of their intracranial aneurysms is often early (between 40 and 60 years) and that their good neurological status should allow "a priori" to return easily at the active life.

Conditions

Intracranial Aneurysm

Outcome Measures

Primary Outcomes (1)

• depression

  Depression evaluated using the Hamilton scale

  6 months

Secondary Outcomes (2)

• tired

  6 months

• anxiety

  6 months

Study Arms (1)

patient with endovascular treatment for intracranial aneurysm

EXPERIMENTAL

Other: questionnaires assessing the state of fatigue, depression and anxiety

Interventions

questionnaires assessing the state of fatigue, depression and anxiety OTHER

patient with endovascular treatment for intracranial aneurysm

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• patient with endovascular treatment for intracranial aneurysm (ruptured or unruptured)
• patient older than 18 years
• patient consenting to participate to the study
• patient enrolled in the national healthcare insurance program

You may not qualify if:

• patient with anterior treatment for intracranial aneurysm
• bipolar disorder, schizophrenia or schizoaffective disorder diagnostic

Sponsors & Collaborators

• CHU de Reims: lead

Study Sites (1)

Chu de Reims

Reims, 51092, France

Location

MeSH Terms

Conditions

Intracranial Aneurysm

Condition Hierarchy (Ancestors)

Intracranial Arterial Diseases; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Aneurysm; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 10, 2016
• First Posted: August 15, 2016
• Study Start: March 17, 2016
• Primary Completion: February 17, 2021
• Study Completion: September 17, 2021
• Last Updated: January 13, 2022

Record last verified: 2021-12

Locations

FR (1)