Communication Bridge Speech Therapy Research Study

NCT02439853 | Completed

• 1 other identifier: IRB23-1336
• Study Type: interventional
• Target: 57
• Locations: 1 country
• Sites: 1

Brief Summary

This is a study on Internet-based video-practice speech and language therapy for persons with primary progressive aphasia (PPA), behavioral-variant frontotemporal dementia (bvFTD), or related conditions.

Conditions

Primary Progressive Aphasia; Frontotemporal Dementia

Keywords

primary progressive aphasia; progressive nonfluent aphasia; progressive aphasia; frontotemporal dementia; frontotemporal lobar degeneration

Outcome Measures

Primary Outcomes (1)

• Assessment of Functional Communication Abilities

  Functional Communication Abilities will be assessed through questionnaires about the participant's language and communication, neuropsychological testing, and speech and language therapy evaluations.

  Change from baseline assessment at 2-months, 6-months and 12-months post-treatment

Study Arms (2)

Check-In group

EXPERIMENTAL

Subjects in the Check-In group will undergo three check-in sessions with the speech therapist. These sessions will happen remotely, via video-chat, and will last less than an hour. They will occur at 3-, 4-, and 5-months from the subject's enrollment date.

Behavioral: Monthly Check-in Session

Control Arm

NO INTERVENTION

Subjects in the Control arm will not undergo three check-in sessions with the speech therapist.

Interventions

Monthly Check-in Session BEHAVIORAL

Subjects in the Check-In group will have an online session with a speech-language pathologist 3-, 4-, and 5-months from the subject's enrollment date.

Check-In group

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosis of dementia with language as a primary symptom (i.e. aphasia)
• An informant who knows the participant well and can answer questions the participant's communication ability
• Adequate hearing to follow conversation (correction permitted)
• Adequate vision (correction permitted)

Sponsors & Collaborators

• University of Chicago: lead
• Alzheimer's Association: collaborator
• The Association for Frontotemporal Degeneration: collaborator
• Illinois Department of Public Health: collaborator
• National Institutes of Health (NIH): collaborator

Study Sites (1)

University of Chicago

Chicago, Illinois, 60637, United States

Location

MeSH Terms

Conditions

Aphasia, Primary Progressive; Frontotemporal Dementia; Primary Progressive Nonfluent Aphasia; Aphasia; Frontotemporal Lobar Degeneration

Condition Hierarchy (Ancestors)

Dementia; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Speech Disorders; Language Disorders; Communication Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Neurocognitive Disorders; Mental Disorders; TDP-43 Proteinopathies; Neurodegenerative Diseases; Proteostasis Deficiencies; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Officials

• Emily J Rogalski, PhD

  University of Chicago

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 23, 2015
• First Posted: May 12, 2015
• Study Start: March 1, 2013
• Primary Completion: December 1, 2019
• Study Completion: January 1, 2020
• Last Updated: September 19, 2024

Record last verified: 2024-09

Locations

US (1)