Key Insights

Highlights

Success Rate

93% trial completion (above average)

Published Results

13 trials with published results (11%)

Research Maturity

53 completed trials (46% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

3.5%

4 terminated out of 115 trials

Success Rate

93.0%

+6.4% vs benchmark

Late-Stage Pipeline

5%

6 trials in Phase 3/4

Results Transparency

25%

13 of 53 completed with results

Key Signals

13 with results93% success

Data Visualizations

Phase Distribution

70Total
Not Applicable (38)
Early P 1 (2)
P 1 (13)
P 2 (11)
P 3 (3)
P 4 (3)

Trial Status

Completed53
Recruiting23
Active Not Recruiting13
Unknown9
Enrolling By Invitation7
Terminated4

Trial Success Rate

93.0%

Benchmark: 86.6%

Based on 53 completed trials

Clinical Trials (115)

Showing 20 of 20 trials
NCT05326750Not ApplicableRecruiting

Non-invasive Neurostimulation as a Tool for Diagnostics and Management for Neurodegenerative Diseases

NCT04374136Phase 3TerminatedPrimary

A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

NCT03225144RecruitingPrimary

Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

NCT05683860Phase 1Terminated

Open-label Extension (OLE) Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) and/or Frontotemporal Dementia (FTD)

NCT04220021Phase 2Active Not Recruiting

Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD

NCT06377033Not ApplicableRecruiting

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

NCT06064890Phase 1RecruitingPrimary

A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

NCT06209515Active Not Recruiting

Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register Study

NCT05742698Phase 2TerminatedPrimary

Nabilone for Agitation in Frontotemporal Dementia

NCT04408625Phase 1Active Not RecruitingPrimary

Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)

NCT07638813Phase 1Not Yet RecruitingPrimary

MSC-Exosome Therapy for Frontotemporal Dementia

NCT02795052Not ApplicableRecruiting

Neurologic Stem Cell Treatment Study

NCT00950430Phase 4Enrolling By Invitation

Imaging of Brain Amyloid Plaques in the Aging Population

NCT04516499Active Not RecruitingPrimary

Neurofilament Surveillance Project (NSP)

NCT04875416Active Not Recruiting

Phenotype, Genotype and Biomarkers 2

NCT02327845Active Not Recruiting

Phenotype, Genotype & Biomarkers in ALS and Related Disorders

NCT03912987Active Not Recruiting

TRIAL READY (Clinical Trial Readiness)

NCT02496312Not ApplicableCompleted

Quantitative Evaluation of Apathy Close to Real Life Situation by Means of a Multimodal Sensor System Integrated.

NCT05779839Not ApplicableActive Not Recruiting

A Study of Caregiver Connections Via Technology in Dementia

NCT04639622Not ApplicableRecruitingPrimary

GENetic Fronto Temporal Dementia Initiative in Lille

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Research Network

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